Novel Immunotherapies for B-Cell Lymphomas and Leukemias

被引：1
|
作者：
Tees, Michael T. [1 ]
Sokol, Lubomir [1 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Hematol, 12902 Magnolia Dr, Tampa, FL 33612 USA
来源：
AMERICAN JOURNAL OF THERAPEUTICS | 2016年 / 23卷 / 05期
关键词：
non-Hodgkin lymphoma; Hodgkin lymphoma; B-cell neoplasms; immunotherapy; radioimmunotherapy; monoclonal antibody; antibody-drug conjugate; NON-HODGKIN-LYMPHOMA; PHASE-I TRIAL; IMMUNOCONJUGATE INOTUZUMAB OZOGAMICIN; MONOCLONAL-ANTIBODY LUCATUMUMAB; INNATE IMMUNE-RESPONSES; OPEN-LABEL; BRENTUXIMAB VEDOTIN; FOLLICULAR LYMPHOMA; CLINICAL ACTIVITY; PLUS RITUXIMAB;
D O I：
10.1097/MJT.0000000000000145
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Current immunotherapeutic agents under investigation have the potential to significantly expand our ability to effectively treat B-cell malignancies. New disease targets, novel strategies to deliver therapy, and advanced agents that work to manipulate the immune system are a few of the ways immunotherapy has quickly evolved. Novel targeted and immune-modifying therapies may demonstrate early potential but unique toxicities and other limitations, such as difficulties in administration, must also be acknowledged. This review provides a comprehensive assessment of the current immunotherapies under investigation against B-cell malignancies.
引用
收藏
页码：E1157 / E1181
页数：25
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