Absence of MGMT promoter methylation in diffuse midline glioma, H3 K27M-mutant

被引:32
|
作者
Banan, Rouzbeh [1 ]
Christians, Arne [1 ]
Bartels, Stephan [2 ]
Lehmann, Ulrich [2 ]
Hartmann, Christian [1 ]
机构
[1] Hannover Med Sch MHH, Inst Pathol, Dept Neuropathol, Carl Neuberg Str 1, D-30625 Hannover, Germany
[2] Hannover Med Sch, Inst Pathol, Hannover, Germany
来源
ACTA NEUROPATHOLOGICA COMMUNICATIONS | 2017年 / 5卷
关键词
Diffuse midline glioma H3 K27M-mutant; H3F3A; HIST1H3B; MGMT; BRAIN-STEM GLIOMAS; GENE-EXPRESSION; GLIOBLASTOMA; MARKERS; ADULTS;
D O I
10.1186/s40478-017-0500-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] H3 K27M-altered glioma and diffuse intrinsic pontine glioma: Semi-systematic review of treatment landscape and future directions
    van den Bent, Martin
    Saratsis, Amanda M.
    Geurts, Marjolein
    Franceschi, Enrico
    NEURO-ONCOLOGY, 2024, 26 : S110 - S124
  • [22] High frequency of H3 K27M mutations in adult midline gliomas
    Ebrahimi, Azadeh
    Skardelly, Marco
    Schuhmann, Martin U.
    Ebinger, Martin
    Reuss, David
    Neumann, Manuela
    Tabatabai, Ghazaleh
    Kohlhof-Meinecke, Patricia
    Schittenhelm, Jens
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2019, 145 (04) : 839 - 850
  • [23] Diffuse non-midline glioma with H3F3A K27M mutation: a prognostic and treatment dilemma
    Lopez, Giselle
    Bush, Nancy Ann Oberheim
    Berger, Mitchel S.
    Perry, Arie
    Solomon, David A.
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2017, 5 : 38
  • [24] Untangling the role of mutant histone H3 in diffuse intrinsic pontine glioma
    Creasy, Caretha L.
    NATURE MEDICINE, 2017, 23 (04) : 413 - 414
  • [25] Epigenetic-Targeted Treatments for H3K27M-Mutant Midline Gliomas
    Lu, Victor M.
    Daniels, David J.
    HISTONE MUTATIONS AND CANCER, 2021, 1283 : 73 - 84
  • [26] Prognostic Implication of Patient Age in H3K27M-Mutant Midline Gliomas
    Huy Gia Vuong
    Ngo, Tam N. M.
    Hieu Trong Le
    Jea, Andrew
    Hrachova, Maya
    Battiste, James
    McNall-Knapp, Rene
    Dunn, Ian F.
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [27] Radiotherapy and radio-sensitization in H3K27M-mutated diffuse midline gliomas
    Liu, Chao
    Kuang, Shuwen
    Wu, Lei
    Cheng, Quan
    Gong, Xuan
    Wu, Jun
    Zhang, Longbo
    CNS NEUROSCIENCE & THERAPEUTICS, 2023, 29 (07) : 1721 - 1737
  • [28] Prediction of H3K27M mutation status of diffuse midline gliomas using MRI features
    Chauhan, Richa Singh
    Kulanthaivelu, Karthik
    Kathrani, Nihar
    Kotwal, Abhishek
    Bhat, Maya Dattatraya
    Saini, Jitender
    Prasad, Chandrajit
    Chakrabarti, Dhritiman
    Santosh, Vani
    Uppar, Alok Mohan
    Srinivas, Dwarakanath
    JOURNAL OF NEUROIMAGING, 2021, 31 (06) : 1201 - 1210
  • [29] Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
    Hanna Gött
    Silke Kiez
    Hildegard Dohmen
    Malgorzata Kolodziej
    Marco Stein
    Child's Nervous System, 2022, 38 : 1791 - 1796
  • [30] Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M-a case report
    Goett, Hanna
    Kiez, Silke
    Dohmen, Hildegard
    Kolodziej, Malgorzata
    Stein, Marco
    CHILDS NERVOUS SYSTEM, 2022, 38 (09) : 1791 - 1796