Proton Therapy in the Treatment of Anal Cancer in Pelvic Kidney Transplant Recipients: A Case Series

被引：6
|
作者：
Buchberger, David [1 ]
Kreinbrink, Paul [1 ]
Kharofa, Jordan [1 ]
机构：
[1] Univ Cincinnati, Dept Radiat Oncol, Med Ctr, 234 Goodman St,ML 0757, Cincinnati, OH 45267 USA
来源：
INTERNATIONAL JOURNAL OF PARTICLE THERAPY | 2019年 / 6卷 / 01期
关键词：
intensity-modulated proton therapy; anal cancer; anal neoplasia; kidney transplant; pelvic kidney; RENAL-TRANSPLANTATION; RANDOMIZED-TRIAL; CARCINOMA; ORGAN; CHEMORADIATION; RADIOTHERAPY; MITOMYCIN; RISK; 5-FLUOROURACIL; CHEMOTHERAPY;
D O I：
10.14338/IJPT-19-00067.1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: The incidence of anal cancer in patients with kidney transplants has increased. The definitive treatment for anal cancer is chemotherapy and intensity-modulated radiation therapy. In kidney transplant recipients, sparing the pelvic kidney in the process of delivering radiation to the anus can be challenging. Intensity-modulated proton therapy (IMPT) has been proposed as an alternative to intensity-modulated radiation therapy for the treatment of anal cancer in this population, given its increased ability to spare organs-at-risk. Case Series: We present 4 cases of patients with transplanted pelvic kidneys who subsequently developed anal cancer and were treated with IMPT from 2017 to 2019. Conclusion: Use of IMPT appears to be an acceptable option for the treatment of anal cancer in patients with a pelvic kidney.
引用
收藏
页码：28 / 34
页数：7
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