Change in seizure threshold during electroconvulsive therapy

被引：27

作者：

Fink, Max

Petrides, Georgios ^{[1
]}

Kellner, Charles ^{[1
]}

Mueller, Martina ^{[2
]}

Knapp, Rebecca ^{[2
]}

Husain, Mustafa M. ^{[3
]}

Rasmussen, Keith ^{[4
]}

Rummans, Teri ^{[4
]}

O'Connor, Kevin ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, Newark, NJ 07103 USA

[2] Med Univ S Carolina, Charleston, SC 29425 USA

[3] Univ Texas Dallas, SW Med Sch, Dallas, TX 75230 USA

[4] Mayo Clin, Rochester, MN USA

来源：

JOURNAL OF ECT | 2008年 / 24卷 / 02期

关键词：

seizure threshold; major depression; bilateral ECT;

D O I：

10.1097/YCT.0b013e31815f65b9

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The seizure threshold (ST) is a measure of the minimum electrical energy necessary to induce a grand mal seizure. Dose titration of the ST has been suggested to optimize stimulus dosing in electroconvulsive therapy (ECT). The change in ST with remission is examined in a large sample of unipolar depressed patients. Methods: In a study of. continuation treatments after successful ECT, the ST was determined at the first treatment and again 1 week after remission using a conventional ST measurement protocol. Patients were treated with bilateral electrode placement at 150% above the measured ST. Results: In 80 subjects, the ST measured the same in 70%, increased in 21%, and decreased in 9% at remission. Conclusions: In a study of bilateral ECT, the ST did not rise conclusively with remission.

引用

页码：114 / 116

页数：3

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