Change in seizure threshold during electroconvulsive therapy

被引：27
|
作者：
Fink, Max
Petrides, Georgios [1 ]
Kellner, Charles [1 ]
Mueller, Martina [2 ]
Knapp, Rebecca [2 ]
Husain, Mustafa M. [3 ]
Rasmussen, Keith [4 ]
Rummans, Teri [4 ]
O'Connor, Kevin [1 ]
机构：
[1] Univ Med & Dent New Jersey, Newark, NJ 07103 USA
[2] Med Univ S Carolina, Charleston, SC 29425 USA
[3] Univ Texas Dallas, SW Med Sch, Dallas, TX 75230 USA
[4] Mayo Clin, Rochester, MN USA
来源：
JOURNAL OF ECT | 2008年 / 24卷 / 02期
关键词：
seizure threshold; major depression; bilateral ECT;
D O I：
10.1097/YCT.0b013e31815f65b9
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The seizure threshold (ST) is a measure of the minimum electrical energy necessary to induce a grand mal seizure. Dose titration of the ST has been suggested to optimize stimulus dosing in electroconvulsive therapy (ECT). The change in ST with remission is examined in a large sample of unipolar depressed patients. Methods: In a study of. continuation treatments after successful ECT, the ST was determined at the first treatment and again 1 week after remission using a conventional ST measurement protocol. Patients were treated with bilateral electrode placement at 150% above the measured ST. Results: In 80 subjects, the ST measured the same in 70%, increased in 21%, and decreased in 9% at remission. Conclusions: In a study of bilateral ECT, the ST did not rise conclusively with remission.
引用
收藏
页码：114 / 116
页数：3
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