Diversity-oriented synthesis of amino acids using chiral enolates

被引:5
作者
Sen, Subhabrata [1 ]
Kamma, Siva R. [1 ]
Potti, Venkata R. [1 ]
Murthy, Y. L. N. [2 ]
Chaudhary, Avinash B. [1 ]
机构
[1] GVK Biosci, Hyderabad, Andhra Pradesh, India
[2] Andhra Univ, Dept Chem Food Drugs & Water, Coll Sci & Technol, Vishakhapatnam, India
关键词
Diversity oriented synthesis; alpha-Amino acid; beta-Amino acid; Mannich reaction; Pluripotent functional group; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; DERIVATIVES; CATALYSIS; CYANIDE;
D O I
10.1016/j.tetlet.2011.08.052
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report a facile diversity oriented synthesis of alpha- and beta-amino acids, by utilizing the pluripotent alpha-methylene group in a chiral bicyclic lactam as our key point of transformation. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5585 / 5588
页数:4
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