Diversity-oriented synthesis of amino acids using chiral enolates

被引：5
作者：
Sen, Subhabrata [1 ]
Kamma, Siva R. [1 ]
Potti, Venkata R. [1 ]
Murthy, Y. L. N. [2 ]
Chaudhary, Avinash B. [1 ]
机构：
[1] GVK Biosci, Hyderabad, Andhra Pradesh, India
[2] Andhra Univ, Dept Chem Food Drugs & Water, Coll Sci & Technol, Vishakhapatnam, India
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 43期
关键词：
Diversity oriented synthesis; alpha-Amino acid; beta-Amino acid; Mannich reaction; Pluripotent functional group; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; DERIVATIVES; CATALYSIS; CYANIDE;
D O I：
10.1016/j.tetlet.2011.08.052
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report a facile diversity oriented synthesis of alpha- and beta-amino acids, by utilizing the pluripotent alpha-methylene group in a chiral bicyclic lactam as our key point of transformation. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5585 / 5588
页数：4
相关论文
共 38 条
  • [1] 1,2-amino alcohols and their heterocyclic derivatives as chiral auxiliaries in asymmetric synthesis
    Ager, DJ
    Prakash, I
    Schaad, DR
    [J]. CHEMICAL REVIEWS, 1996, 96 (02) : 835 - 875
  • [2] [Anonymous], ASSYMETRICSYNTHESIS
  • [3] [Anonymous], JOC
  • [4] [Anonymous], J AM CHEM SOC
  • [5] [Anonymous], J CHEM SOC P1
  • [6] A planning strategy for diversity-oriented synthesis
    Burke, MD
    Schreiber, SL
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (01) : 46 - 58
  • [7] Recent progress on the stereoselective synthesis of acyclic quaternary α-amino acids
    Cativiela, Carlos
    Diaz-de-Villegas, Maria D.
    [J]. TETRAHEDRON-ASYMMETRY, 2007, 18 (05) : 569 - 623
  • [8] Asymmetric Strecker synthesis using enantiopure sulfinimines and diethylaluminum cyanide: The alcohol effect
    Davis, FA
    Portonovo, PS
    Reddy, RE
    Chiu, YH
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (02) : 440 - 441
  • [9] RECENT DEVELOPMENTS IN THE STEREOSELECTIVE SYNTHESIS OF ALPHA-AMINO-ACIDS
    DUTHALER, RO
    [J]. TETRAHEDRON, 1994, 50 (06) : 1539 - 1650
  • [10] Galloway W. R. J. D., 2010, NATURE COMMON, P1
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