Endometriosis: A Disease with Few Direct Treatment Options

被引：42
作者：
Franca, Patricia Ribeiro de Carvalho [1 ]
Lontra, Anna Carolina Pereira [1 ]
Fernandes, Patricia Dias [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Inst Ciencias Biomed, Lab Farmacol Dor & Inflamacao, BR-21941902 Rio De Janeiro, Brazil
来源：
MOLECULES | 2022年 / 27卷 / 13期
关键词：
endometriosis; gynecological disease; inflammation; drug therapy; DENDRITIC CELL-POPULATIONS; FACTOR-KAPPA-B; STROMAL CELLS; EUTOPIC ENDOMETRIUM; LYMPH-NODES; STEM-CELLS; PATHOGENESIS; EXPRESSION; DIAGNOSIS; CYTOKINES;
D O I：
10.3390/molecules27134034
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility in addition to high treatment costs. Currently, available medications are only effective in treating endometriosis-related pain; however, it is not a targeted treatment. The objective of this work is to review the characteristics of the disease, the diagnostic means and treatments available, as well as to discuss new therapeutic options.
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页数：20
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共 133 条
  • [91] The role of prostaglandin E2 in endometriosis
    Sacco, Keith
    Portelli, Mark
    Pollacco, Joel
    Schembri-Wismayer, Pierre
    Calleja-Agius, Jean
    [J]. GYNECOLOGICAL ENDOCRINOLOGY, 2012, 28 (02) : 134 - 138
  • [92] Is the oocyte quality affected by endometriosis? A review of the literature
    Sanchez, Ana Maria
    Vanni, Valeria Stella
    Bartiromo, Ludovica
    Papaleo, Enrico
    Zilberberg, Eran
    Candiani, Massimo
    Orvieto, Raoul
    Vigano, Paola
    [J]. JOURNAL OF OVARIAN RESEARCH, 2017, 10
  • [93] Stem cells and the pathogenesis of endometriosis
    Sasson, Isaac E.
    Taylor, Hugh S.
    [J]. ASSESSMENT OF HUMAN REPRODUCTIVE FUNCTION, 2008, 1127 : 106 - 115
  • [94] Dendritic cell populations in the eutopic and ectopic endometrium of women with endometriosis
    Schulke, Lauren
    Berbic, Marina
    Manconi, Frank
    Tokushige, Natsuko
    Markham, Robert
    Fraser, Ian S.
    [J]. HUMAN REPRODUCTION, 2009, 24 (07) : 1695 - 1703
  • [95] NK Cells as Potential Targets for Immunotherapy in Endometriosis
    Sciezynska, Aneta
    Komorowski, Michal
    Soszynska, Marta
    Malejczyk, Jacek
    [J]. JOURNAL OF CLINICAL MEDICINE, 2019, 8 (09)
  • [96] Shah Ruchi, 2018, Critical Reviews in Biomedical Engineering, V46, P277, DOI 10.1615/CritRevBiomedEng.2018027414
  • [97] Obstetrical and neonatal outcomes of pregnancies complicated by endometriosis
    Shmueli, Anat
    Salman, Lina
    Hiersch, Liran
    Ashwal, Eran
    Hadar, Eran
    Wiznitzer, Arnon
    Yogev, Yariv
    Aviram, Amir
    [J]. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2019, 32 (05) : 845 - 850
  • [98] Methylation analysis of HOXA10 regulatory elements in patients with endometriosis
    Signorile P.G.
    Severino A.
    Santoro M.
    Spyrou M.
    Viceconte R.
    Baldi A.
    [J]. BMC Research Notes, 11 (1)
  • [99] The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres
    Simoens, Steven
    Dunselman, Gerard
    Dirksen, Carmen
    Hummelshoj, Lone
    Bokor, Attila
    Brandes, Iris
    Brodszky, Valentin
    Canis, Michel
    Colombo, Giorgio Lorenzo
    DeLeire, Thomas
    Falcone, Tommaso
    Graham, Barbara
    Halis, Guelden
    Horne, Andrew
    Kanj, Omar
    Kjer, Jens Jorgen
    Kristensen, Jens
    Lebovic, Dan
    Mueller, Michael
    Vigano, Paola
    Wullschleger, Marcel
    D'Hooghe, Thomas
    [J]. HUMAN REPRODUCTION, 2012, 27 (05) : 1292 - 1299
  • [100] Simpson Joe Leigh, 2003, Obstet Gynecol Clin North Am, V30, P21, DOI 10.1016/S0889-8545(02)00051-7
567891011121314