Pd-Catalyzed Cyanation of (Hetero)Aryl Halides by Using Biphosphine Ligands

被引：23

作者：

Zhang, Shaoke ^{[1
]}

Neumann, Helfried ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29 A, D-18059 Rostock, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2018年 / 24卷 / 01期

关键词：

aryl halides; biphosphines; cyanation; palladium; synthetic methods; OLEFIN METATHESIS CATALYSTS; SECONDARY PHOSPHINE OXIDES; H BOND ACTIVATION; ARYL CHLORIDES; CONVENIENT PROCEDURE; EFFICIENT CATALYSTS; PHASE AMMOXIDATION; ARYLBORONIC ACIDS; PINCER COMPLEXES; CROSS-COUPLINGS;

D O I：

10.1002/chem.201704178

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tetraadamantylbiphosphine (TABP; L1), which showed superior activity in the palladium-catalyzed cyanation of 4-chloroanisole compared to standard phosphines, was synthesized as a new ligand. The generality of the new catalytic system was shown by the cyanation reaction of approximately 30(hetero)aryl halides including hindered, electron-rich, and electron-poor aryl chlorides. These reactions constitute the first examples of using bi-phosphine ligands in Pd-catalyzed coupling reactions.

引用

页码：67 / 70

页数：4

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