EXPERIMENTAL AND THEORETICAL INVESTIGATIONS ON THE STRUCTURE AND PROPERTIES OF A HYDRAZINE CRYSTAL AND ITS ANTIBACTERIAL EFFECTS

被引：4
作者：
Lu, Lunwen [1 ]
Qin, Wanguang G. [1 ]
机构：
[1] Hunan Mech & Elect Polytech, Dept Biol & Chem Engn, Changsha, Hunan, Peoples R China
来源：
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT | 2011年 / 25卷 / 03期
关键词：
hydrazine; IR; Raman; DFT calculations; antibacterial activity;
D O I：
10.5504/BBEQ.2011.0055
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The crystal of 1,2-bis (ethoxycarbonyl) hydrazine was synthesized by the reaction of hydrazine hydrate and ethyl chloroformate. Its crystallographic structure was characterized using XRD, FTIR and Raman spectroscopy. The antibacterial activities of the compound against the two bacteria- Staphylococcus aureus and Escherichia coli, were investigated. Based on experimental results, the ground-state geometries were optimized using density-functional theory (DFT) at B3LYP/6-31G (d, p) without symmetry constrains, and the vibrational wavenumbers were calculated at the same level. Biotechnol. & Biotechnol. Eq. 2011, 25(3), 2528-2532
引用
收藏
页码：2528 / 2532
页数：5
相关论文
共 13 条
  • [1] DENSITY-FUNCTIONAL THERMOCHEMISTRY .3. THE ROLE OF EXACT EXCHANGE
    BECKE, AD
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1993, 98 (07) : 5648 - 5652
  • [2] Pleuromutilins. Part 1: The identification of novel mutilin 14-carbamates
    Brooks, G
    Burgess, W
    Colthurst, D
    Hinks, JD
    Hunt, E
    Pearson, MJ
    Shea, B
    Takle, AK
    Wilson, JM
    Woodnutt, G
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (05) : 1221 - 1231
  • [3] STUDIES ON ASYMMETRIC SYNTHESIS OF ALPHA-AMINO ACIDS .2. NEW SYSTEMS FOR HIGHLY SPECIFIC ASYMMETRIC SYNTHESIS WITH CONSERVATION OF CHIRAL REAGENT
    COREY, EJ
    SACHDEV, HS
    GOUGOUTAS, JZ
    SAENGER, W
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (08) : 2488 - +
  • [4] Enders D., 1984, ASYMMETRIC SYNTHESIS, V3, P275
  • [5] Frisch M. J., 2004, GAUSSIAN03 REVISION, P7
  • [6] *GAUSS INC, 2004, GAUSSVIEW 3 0
  • [7] Hehre W.J., 1986, Abinitio molecular orbital theory
  • [8] KANIA RS, 2001, Patent No. 0102369
  • [9] KATRITZKY AR, 1984, COMPREHENSIVE HETERO, V1, P313
  • [10] MURAKAMI Y, 2000, Patent No. 200026869
12