Prevention and treatment of relapse after stem cell transplantation in lymphoid malignancies

被引：4
作者：
Sureda, Anna [1 ]
Dreger, Peter [2 ,3 ]
Bishop, Michael R. [4 ]
Kroger, Nicolaus [5 ]
Porter, David L. [6 ,7 ]
机构：
[1] Hosp Barcelona, Inst Catala Oncol, Hematol Dept, Barcelona, Spain
[2] Heidelberg Univ, Dept Med 5, Heidelberg, Germany
[3] European Soc Blood & Marrow Transplantat EBMT, Leiden, Netherlands
[4] Univ Chicago, Hematopoiet Cellular Therapy Program, Sect Hematol Oncol, Chicago, IL 60637 USA
[5] Univ Med Ctr, Dept Stem Cell Transplantat, Hamburg, Germany
[6] Univ Penn, Div Hematol Oncol, Blood & Marrow Transplant Program, Philadelphia, PA 19104 USA
[7] Perelman Sch Med, Philadelphia, PA 19104 USA
来源：
BONE MARROW TRANSPLANTATION | 2019年 / 54卷 / 01期
关键词：
CHRONIC LYMPHOCYTIC-LEUKEMIA; DIAGNOSED MULTIPLE-MYELOMA; PROGRAMMED DEATH-1 BLOCKADE; 2ND INTERNATIONAL WORKSHOP; HIGH-DOSE CHEMOTHERAPY; BRENTUXIMAB VEDOTIN; CONSOLIDATION THERAPY; ALLOGENEIC TRANSPLANTATION; CONDITIONING REGIMENS; HODGKINS LYMPHOMA;
D O I：
10.1038/s41409-018-0214-5
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Relapse is now the major cause of treatment failure after allogeneic HSCT (alloHSCT). Many novel strategies to address this critical issue are now being developed and tested. At the 3rd International Workshop on Biology, Prevention, and Treatment of Relapse held in Hamburg, Germany in November 2016, international experts presented and discussed recent developments in the field. Some approaches may be applicable to a wide range of patients after transplant, whereas some may be very disease-specific. We present a report from the session dedicated to issues related to prevention and treatment of relapse of lymphoid malignancies after alloHSCT. This session included detailed reviews as well as forward-looking commentaries that focused on Hodgkin lymphoma, chronic lymphocytic leukemia and mantle cell lymphoma, diffuse large cell and follicular lymphoma, and multiple myeloma.
引用
收藏
页码：17 / 25
页数：9
相关论文
共 83 条
  • [51] Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma:: final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial
    Moreau, P
    Facon, T
    Attal, M
    Hulin, C
    Michallet, M
    Maloisel, F
    Sotto, JJ
    Guilhot, F
    Marit, G
    Doyen, C
    Jaubert, A
    Fuzibet, JG
    François, S
    Benboubker, L
    Monconduit, M
    Voillat, L
    Macro, M
    Berthou, C
    Dorvaux, V
    Pignon, B
    Rio, B
    Matthes, T
    Casassus, P
    Caillot, D
    Najman, N
    Grosbois, B
    Bataille, R
    Harousseau, JL
    [J]. BLOOD, 2002, 99 (03) : 731 - 735
  • [52] Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial
    Moskowitz, Craig H.
    Nademanee, Auayporn
    Masszi, Tamas
    Agura, Edward
    Holowiecki, Jerzy
    Abidi, Muneer H.
    Chen, Andy I.
    Stiff, Patrick
    Gianni, Alessandro M.
    Carella, Angelo
    Osmanov, Dzhelil
    Bachanova, Veronika
    Sweetenham, John
    Sureda, Anna
    Huebner, Dirk
    Sievers, Eric L.
    Chi, Andy
    Larsen, Emily K.
    Hunder, Naomi N.
    Walewski, Jan
    [J]. LANCET, 2015, 385 (9980) : 1853 - 1862
  • [53] Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma
    Palumbo, Antonio
    Chanan-Khan, Asher
    Weisel, Katja
    Nooka, Ajay K.
    Masszi, Tamas
    Beksac, Meral
    Spicka, Ivan
    Hungria, Vania
    Munder, Markus
    Mateos, Maria V.
    Mark, Tomer M.
    Qi, Ming
    Schecter, Jordan
    Amin, Himal
    Qin, Xiang
    Deraedt, William
    Ahmadi, Tahamtan
    Spencer, Andrew
    Sonneveld, Pieter
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (08) : 754 - 766
  • [54] Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report
    Passweg, J. R.
    Baldomero, H.
    Bader, P.
    Bonini, C.
    Duarte, R. F.
    Dufour, C.
    Gennery, A.
    Kroeger, N.
    Kuball, J.
    Lanza, F.
    Montoto, S.
    Nagler, A.
    Snowden, J. A.
    Styczynski, J.
    Mohty, M.
    [J]. BONE MARROW TRANSPLANTATION, 2017, 52 (06) : 811 - 817
  • [55] Rituximab Purging and/or Maintenance in Patients Undergoing Autologous Transplantation for Relapsed Follicular Lymphoma: A Prospective Randomized Trial From the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation
    Pettengell, Ruth
    Schmitz, Norbert
    Gisselbrecht, Christian
    Smith, Graeme
    Patton, William N.
    Metzner, Bernd
    Caballero, Dolores
    Tilly, Herve
    Walewski, Jan A.
    Bence-Bruckler, Isabelle
    To, Bik
    Geisler, Christian H.
    Schots, Rik
    Kimby, Eva
    Taverna, Christian J.
    Kozak, Tomas
    Dreger, Peter
    Uddin, Ruzena
    de Elvira, Carmen Ruiz
    Goldstone, Anthony H.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (13) : 1624 - +
  • [56] NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    Porter, David L.
    Alyea, Edwin P.
    Antin, Joseph H.
    DeLima, Marcos
    Estey, Eli
    Falkenburg, J. H. Frederik
    Hardy, Nancy
    Kroeger, Nicolaus
    Leis, Jose
    Levine, John
    Maloney, David G.
    Peggs, Karl
    Rowe, Jacob M.
    Wayne, Alan S.
    Giralt, Sergio
    Bishop, Michael R.
    van Besien, Koen
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (11) : 1467 - 1503
  • [57] CAR T-Cell Therapy in Large B-Cell Lymphoma
    Quintas-Cardama, Alfonso
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (11) : 1065 - 1065
  • [58] Unmanipulated haploidentical BMT following non-myeloablative conditioning and post-transplantation CY for advanced Hodgkin's lymphoma
    Raiola, A.
    Dominietto, A.
    Varaldo, R.
    Ghiso, A.
    Galaverna, F.
    Bramanti, S.
    Todisco, E.
    Sarina, B.
    Giordano, L.
    Ibatici, A.
    Santoro, A.
    Clavio, M.
    Bacigalupo, A.
    Castagna, L.
    [J]. BONE MARROW TRANSPLANTATION, 2014, 49 (02) : 190 - 194
  • [59] Risk-stratified adoptive cellular therapy following allogeneic hematopoietic stem cell transplantation for advanced chronic lymphocytic leukaemia
    Richardson, Simon E.
    Khan, Iftekhar
    Rawstron, Andrew
    Sudak, Jagoda
    Edwards, Noha
    Verfuerth, Stephanie
    Fielding, Adele K.
    Goldstone, Anthony
    Kottaridis, Panagiotis
    Morris, Emma
    Benjamin, Reuben
    Peggs, Karl S.
    Thomson, Kirsty J.
    Vandenberghe, Elisabeth
    Mackinnon, Stephen
    Chakraverty, Ronjon
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (05) : 640 - 648
  • [60] Allogeneic hematopoietic stem cell transplantation in patients with diffuse large B cell lymphoma relapsed after autologous stem cell transplantation: A GITMO study
    Rigacci, Luigi
    Puccini, Bendetta
    Dodero, Anna
    Iacopino, Pasquale
    Castagna, Luca
    Bramanti, Stefania
    Ciceri, Fabio
    Fanin, Renato
    Rambaldi, Alessandro
    Falda, Michele
    Milone, Giuseppe
    Guidi, Stefano
    Martelli, Massimo Fabrizio
    Mazza, Patrizio
    Oneto, Rosi
    Bosi, Alberto
    [J]. ANNALS OF HEMATOLOGY, 2012, 91 (06) : 931 - 939
123456789