Prevention and treatment of relapse after stem cell transplantation in lymphoid malignancies

被引:4
作者
Sureda, Anna [1 ]
Dreger, Peter [2 ,3 ]
Bishop, Michael R. [4 ]
Kroger, Nicolaus [5 ]
Porter, David L. [6 ,7 ]
机构
[1] Hosp Barcelona, Inst Catala Oncol, Hematol Dept, Barcelona, Spain
[2] Heidelberg Univ, Dept Med 5, Heidelberg, Germany
[3] European Soc Blood & Marrow Transplantat EBMT, Leiden, Netherlands
[4] Univ Chicago, Hematopoiet Cellular Therapy Program, Sect Hematol Oncol, Chicago, IL 60637 USA
[5] Univ Med Ctr, Dept Stem Cell Transplantat, Hamburg, Germany
[6] Univ Penn, Div Hematol Oncol, Blood & Marrow Transplant Program, Philadelphia, PA 19104 USA
[7] Perelman Sch Med, Philadelphia, PA 19104 USA
关键词
CHRONIC LYMPHOCYTIC-LEUKEMIA; DIAGNOSED MULTIPLE-MYELOMA; PROGRAMMED DEATH-1 BLOCKADE; 2ND INTERNATIONAL WORKSHOP; HIGH-DOSE CHEMOTHERAPY; BRENTUXIMAB VEDOTIN; CONSOLIDATION THERAPY; ALLOGENEIC TRANSPLANTATION; CONDITIONING REGIMENS; HODGKINS LYMPHOMA;
D O I
10.1038/s41409-018-0214-5
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Relapse is now the major cause of treatment failure after allogeneic HSCT (alloHSCT). Many novel strategies to address this critical issue are now being developed and tested. At the 3rd International Workshop on Biology, Prevention, and Treatment of Relapse held in Hamburg, Germany in November 2016, international experts presented and discussed recent developments in the field. Some approaches may be applicable to a wide range of patients after transplant, whereas some may be very disease-specific. We present a report from the session dedicated to issues related to prevention and treatment of relapse of lymphoid malignancies after alloHSCT. This session included detailed reviews as well as forward-looking commentaries that focused on Hodgkin lymphoma, chronic lymphocytic leukemia and mantle cell lymphoma, diffuse large cell and follicular lymphoma, and multiple myeloma.
引用
收藏
页码:17 / 25
页数:9
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