Recent developments in electrospray ionisation mass spectrometry: noncovalently bound protein complexes

被引:44
|
作者
Ashcroft, AE [1 ]
机构
[1] Univ Leeds, Sch Biochem & Microbiol, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England
关键词
D O I
10.1039/b417724j
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Noncovalently bound macromolecular protein complexes constitute an essential aspect of the living cell and are responsible for many biological processes. This review focuses on the analysis of these important species by electrospray ionisation mass spectrometry. The current range of instrumentation is discussed and the major biological complexes studied to date are highlighted. This review has 108 references.
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页码:452 / 464
页数:13
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