Recent developments in electrospray ionisation mass spectrometry: noncovalently bound protein complexes

被引：44

作者：

Ashcroft, AE ^{[1
]}

机构：

[1] Univ Leeds, Sch Biochem & Microbiol, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England

来源：

NATURAL PRODUCT REPORTS | 2005年 / 22卷 / 04期

关键词：

D O I：

10.1039/b417724j

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Noncovalently bound macromolecular protein complexes constitute an essential aspect of the living cell and are responsible for many biological processes. This review focuses on the analysis of these important species by electrospray ionisation mass spectrometry. The current range of instrumentation is discussed and the major biological complexes studied to date are highlighted. This review has 108 references.

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页码：452 / 464

页数：13

相关论文

共 110 条

[1] Evaluation of protein-DNA binding affinity by electrospray ionization mass spectrometry [J].

Akashi, S ;

Osawa, R ;

Nishimura, Y .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2005, 16 (01) :116-125

[2] Structural plasticity and noncovalent substrate binding in the GroEL apical domain - A study using electrospray ionization mass spectrometry and fluorescence binding studies [J].

Ashcroft, AE ;

Brinker, A ;

Coyle, JE ;

Weber, F ;

Kaiser, M ;

Moroder, L ;

Parsons, MR ;

Jager, J ;

Hartl, UF ;

Hayer-Hartl, M ;

Radford, SE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (36) :33115-33126

[3]

ASHCROFT AE, 2005, IN PRESS J NANOSCI N

[4] Charge-reduced nano electrospray ionization combined with differential mobility analysis of peptides, proteins, glycoproteins, noncovalent protein complexes and viruses [J].

Bacher, G ;

Szymanski, WW ;

Kaufman, SL ;

Zöllner, P ;

Blaas, D ;

Allmaier, G .

JOURNAL OF MASS SPECTROMETRY, 2001, 36 (09) :1038-1052

[5] Thermal dissociation of multimeric protein complexes by using nanoelectrospray mass spectrometry [J].

Benesch, JLP ;

Sobott, F ;

Robinson, CV .

ANALYTICAL CHEMISTRY, 2003, 75 (10) :2208-2214

[6] Mass spectrometry of ribosomes and ribosomal subunits [J].

Benjamin, DR ;

Robinson, CV ;

Hendrick, JP ;

Hartl, FU ;

Dobson, CM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (13) :7391-7395

[7] Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry [J].

Benkestock, K ;

Sundqvist, G ;

Edlund, PO ;

Roeraade, J .

JOURNAL OF MASS SPECTROMETRY, 2004, 39 (09) :1059-1067

[8] Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry [J].

Bligh, SWA ;

Haley, T ;

Lowe, PN .

JOURNAL OF MOLECULAR RECOGNITION, 2003, 16 (03) :139-147

[9] Co-populated conformational ensembles of β2-microglobulin uncovered quantitatively by electrospray ionization mass spectrometry [J].

Borysik, AJH ;

Radford, SE ;

Ashcroft, AE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (26) :27069-27077

[10] New mass spectrometric methods for the quantification of protein-ligand binding in solution [J].

Breuker, K .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (01) :22-25

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