In Phantom Validation of Time-Domain Near-Infrared Optical Tomography Pioneer for Imaging Brain Hypoxia and Hemorrhage

被引：2

作者：

Jiang, J. ^{[1
,2
]}

Lindner, S. ^{[1
,2
,3
]}

Di Costanzo-Mata, A. ^{[1
,2
]}

Zhang, C. ^{[4
]}

Charbon, E. ^{[3
,4
]}

Wolf, M. ^{[1
,2
]}

Kalyanov, A. ^{[1
,2
]}

机构：

[1] Univ Zurich, Dept Neonatol, Biomed Opt Res Lab BORL, Zurich, Switzerland

[2] Univ Hosp Zurich, Zurich, Switzerland

[3] EPFL Lausanne, Adv Quantum Architecture AQUA Lab, Sch Engn, Lausanne, Switzerland

[4] Delft Univ Technol, Appl Quantum Architectures, Delft, Netherlands

来源：

OXYGEN TRANSPORT TO TISSUE XLII | 2021年 / 1269卷

基金：

瑞士国家科学基金会;

关键词：

Time-domain near-infrared optical tomography (TD NITOR); Diffuse optical tomography; Tissue optical properties reconstruction; Tissue oxygenation; Preterm brain imaging; RECONSTRUCTION; PRETERM;

D O I：

10.1007/978-3-030-48238-1_54

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The neonatal brain is a vulnerable organ, and lesions due to hemorrhage and/or ischemia occur frequently in preterm neonates. Even though neuroprotective therapies exist, there is no tool available to detect the ischemic lesions. To address this problem, we have recently designed and built the new time-domain near-infrared optical tomography (TD NIROT) system - Pioneer. Here we present the results of a phantom study of the system performance. We used silicone phantoms to mimic risky situations for brain lesions: hemorrhage and hypoxia. Employing Pioneer, we were able to reconstruct accurately both position and optical properties of these inhomogeneities.

引用

页码：341 / 346

页数：6

共 50 条

[41] Brain imaging in awake infants by near-infrared optical topography
Taga, G
Asakawa, K
Maki, A
Konishi, Y
Koizumi, H
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (19) : 10722 - 10727
[42] Transmission in near-infrared optical windows for deep brain imaging
Shi, Lingyan
Sordillo, Laura A.
Rodriguez-Contreras, Adrian
Alfano, Robert
JOURNAL OF BIOPHOTONICS, 2016, 9 (1-2) : 38 - 43
[43] Imaging of in vitro chicken leg using time-resolved near-infrared optical tomography
Zhao, HJ
Gao, F
Tanikawa, Y
Onodera, Y
Ohmi, M
Haruna, M
Yamada, Y
PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (11): : 1979 - 1993
[44] Diffuser-aided time-domain diffuse optical imaging: a phantom study
Sun, Chia-Wei
Chuang, Ching-Cheng
Lee, Chia-Yen
Chen, Chung-Ming
JOURNAL OF BIOMEDICAL OPTICS, 2014, 19 (04)
[45] Near-infrared imaging and optical coherence tomography for intraoperative visualization of tumors
Holt, David
Singhal, Sunil
Selmic, Laura E.
VETERINARY SURGERY, 2020, 49 (01) : 33 - 43
[46] Development and Validation of a Sensor Prototype for Near-Infrared Imaging of the Newborn Brain
Ahnen, Linda
Stachel, Helene
Kleiser, Stefan
Hagmann, Cornelia
Jiang, Jingjing
Kalyanov, Alexander
Lindner, Scott
Wolf, Martin
Sanchez, Salvador
OXYGEN TRANSPORT TO TISSUE XXXIX, 2017, 977 : 163 - 168
[47] Time-Domain Near-Infrared Spectroscopy in Acute Ischemic Stroke Patients.
Giacalone, Giacomo
Zanoletti, Marta
Re, Rebecca
Germinario, Bruno
Contini, Davide
Spinelli, Lorenzo
Torricelli, Alessandro
Roveri, Luisa
STROKE, 2019, 50
[48] Cerebral Perfusion in Acute Stroke Monitored by Time-domain Near-infrared Reflectometry
Steinkellner, Oliver
Wabnitz, Heidrun
Jelzow, Alexander
Macdonald, Rainer
Gruber, Clemens
Steinbrink, Jens
Obrig, Hellmuth
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING, 2012, 32 (01) : 3 - 16
[49] Continuous time-domain analysis of cerebrovascular autoregulation using near-infrared spectroscopy
Brady, Ken M.
Lee, Jennifer K.
Kibler, Kathleen K.
Smielewski, Piotr
Czosnyka, Marek
Easley, R. Blaine
Koehler, Raymond C.
Shaffner, Donald H.
STROKE, 2007, 38 (10) : 2818 - 2825
[50] Time-domain near-infrared spectroscopy in subjects with cerebral small vessel disease
Giacalone, G.
Zanoletti, M.
Re, R.
Contini, D.
Spinelli, L.
Torricelli, A.
Roveri, L.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 396 - 396

← 1 2 3 4 5 →