Illness severity indicators in newborns by COVID-19 status in the United States, March-December 2020

被引:4
|
作者
Wallace, Bailey [1 ]
Chang, Daniel [1 ,2 ]
Woodworth, Kate [1 ]
DeSisto, Carla L. [1 ]
Simeone, Regina [1 ]
Ko, Jean Y. [1 ,3 ]
Tong, Van T. [1 ]
Gilboa, Suzanne M. [1 ]
Ellington, Sascha R. [1 ]
机构
[1] Ctr Dis Control & Prevent, COVID 19 Response, Atlanta, GA 30333 USA
[2] US DOE, Oak Ridge Inst Sci & Educ, Oak Ridge, TN USA
[3] US Publ Hlth Serv Commissioned Corps, Rockville, MD USA
关键词
ETHNICITY; CARE; RACE; DISPARITIES; SEPSIS; BURDEN;
D O I
10.1038/s41372-021-01243-y
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective To better understand COVID-19 in newborns, we compared in-hospital illness severity indicators by COVID-19 status during birth hospitalization. Study design In a retrospective cohort of newborns born March-December 2020 in the Premier Healthcare Database Special COVID-19 Release, we classified COVID-19 status and severe illness indicators using ICD-CM-10 codes, laboratory data, and billing records. Illness severity indicators were compared by COVID-19 status, stratified by gestational age and race/ethnicity. Result Among 701,777 newborns, 209 had a COVID-19 diagnosis during the birth hospitalization. COVID-19 status differed significantly by race/ethnicity, gestational age, payor, and region. Late preterm/term newborns with COVID-19 had increased intensive care unit admission and sepsis risk; early preterm newborns with COVID-19 had increased risk for invasive ventilation. Risk for illness severity varied among racial/ethnic strata. Conclusion From March to December 2020, COVID-19 diagnosis in newborns was rare. More clinical data are needed to describe the risk profiles of newborns with COVID-19.
引用
收藏
页码:446 / 453
页数:8
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