A facile synthesis of naturally occurring 5-(3-indolyl)oxazoles

被引：36

作者：

Kumar, Dalip ^{[1
]}

Sundaree, Swapna ^{[1
]}

Patel, Gautam ^{[1
]}

Rao, V. S. ^{[1
]}

机构：

[1] Birla Inst Technol & Sci, Chem Grp, Pilani 333031, Rajasthan, India

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 05期

关键词：

5-(3-indolyl)oxazoles; hydroxy(tosyloxy)-iodobenzene; alpha-acylaminoketones; p-toluenesulfonic-acid;

D O I：

10.1016/j.tetlet.2007.11.173

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient synthesis of naturally occurring 5-(3-indolyl)oxazoles is described. The key steps of this convergent approach are the formation of a 3-tosyloxyacetyl-1-benzenesulfonylindole, a 3-amino-acetyl-l-benzenesulfonylindole hydrochloride and cyclodehydration of an alpha-acylaminoketone. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：867 / 869

页数：3

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