Occurrence of a spinal anaplastic pilocytic astrocytoma and a supratentorial PNET in an adolescent

被引：6

作者：

Blankenburg, Friederike ^{[1
]}

van Landeghem, Frank K. H. ^{[2
]}

Plotkin, Michail ^{[3
]}

Henze, Guenter ^{[1
]}

von Deimling, Andreas ^{[4
]}

Driever, Pablo Hernaiz ^{[1
]}

机构：

[1] Univ Med Berlin, Charite, Dept Pediat Oncol & Hematol, D-13353 Berlin, Germany

[2] Univ Med Berlin, Charite, Inst Neuropathol, D-13353 Berlin, Germany

[3] Univ Med Berlin, Charite, Dept Radiol & Nucl Med, D-13353 Berlin, Germany

[4] Univ Klinikum Heidelberg, Dept Neuropathol, D-69120 Heidelberg, Germany

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2007年 / 29卷 / 12期

关键词：

anaplastic pilocytic astrocytoma; supratentorial PNET; TP53; WHO nomenclature;

D O I：

10.1097/MPH.0b013e3181580eb3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 15-year-old girl was diagnosed with a spinal anaplastic pilocytic astrocytoma. The histologic features were similar to pilocytic astrocytoma WHO grade 1, but with an increased mitotic rate, high nuclear pleomorphism, microvascular proliferation, and necrosis. The tumor was subtotally resected and treated with chemotherapy and irradiation. Four years after diagnosis no local progression was seen. At the age of 17, the patient developed a supratentorial primitive neuroectodermal tumor. We report the first case of a primary anaplastic pilocytic astrocytoma and primary primitive neuroectodermal tumor occurring in the same patient.

引用

页码：832 / 835

页数：4

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