Assessing long-term maintenance of efficacy with tralokinumab monotherapy in patients with moderate-to-severe atopic dermatitis: combined results from two phase III, randomized, double-blind, placebo-controlled trials (ECZTRA 1 and 2)

被引：0
|
作者：
Blauvelt, A. [1 ]
Wollenberg, A. [2 ]
Pink, A. [3 ]
Peris, K. [4 ,5 ]
Armstrong, A. [6 ]
Spelman, L. [7 ,8 ]
Saeki, H. [9 ]
Lynde, C. [10 ,11 ]
Herranz, P. [12 ]
Barbarot, S. [13 ]
Simpson, E. [14 ]
机构：
[1] Oregon Med Res Ctr, Portland, OR USA
[2] Ludwig Maximilian Univ Munich, Dept Dermatol & Allergol, Munich, Germany
[3] Guys & St Thomas Hosp, St Johns Inst Dermatol, London, England
[4] Catholic Univ, Dermatol, Rome, Italy
[5] IRCCS, Fdn Policlin Univ A Gemelli, Rome, Italy
[6] Univ Southern Calif, Keck Sch Med, Dept Dermatol, Los Angeles, CA 90007 USA
[7] Verac Clin Res, Brisbane, Qld, Australia
[8] Prob Med Res, Woolloongabba, Qld, Australia
[9] Nippon Med Sch, Dept Dermatol, Tokyo, Japan
[10] Prob Med Res, Lynde Dermatol, Markham, ON, Canada
[11] Univ Toronto, Dept Med, Toronto, ON, Canada
[12] Hosp Univ La Paz, Dept Dermatol, Madrid, Spain
[13] Ctr Hosp Univ Nantes, Nantes, France
[14] Oregon Hlth & Sci Univ, Dept Dermatol, Portland, OR 97201 USA
来源：
BRITISH JOURNAL OF DERMATOLOGY | 2021年 / 185卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
447
引用
收藏
页码：E110 / E111
页数：2
相关论文
共 50 条
  • [21] Efficacy and safety of CM310 in moderate-to-severe atopic dermatitis: A multicenter, randomized, double-blind, placebo-controlled phase 2b trial
    Zhao, Yan
    Zhang, Jianzhong
    Yang, Bin
    Li, Jingyi
    Ding, Yangfeng
    Wu, Liming
    Zhang, Litao
    Wang, Jinyan
    Zhu, Xiaohong
    Zhang, Furen
    Tao, Xiaohua
    Li, Yumei
    Zhang, Chunlei
    Li, Linfeng
    Lu, Jianyun
    Diao, Qingchun
    Lu, Qianjin
    Man, Xiaoyong
    Li, Fuqiu
    Xia, Xiujuan
    Cheng, Hao
    Jia, Yingmin
    Zhao, Guoqing
    Yan, Jinchun
    Chen, Bo
    CHINESE MEDICAL JOURNAL, 2024, 137 (02) : 200 - 208
  • [22] Efficacy and safety of CM310 in moderate-to-severe atopic dermatitis: A multicenter, randomized, double-blind, placebo-controlled phase 2b trial
    Zhao Yan
    Zhang Jianzhong
    Yang Bin
    Li Jingyi
    Ding Yangfeng
    Wu Liming
    Zhang Litao
    Wang Jinyan
    Zhu Xiaohong
    Zhang Furen
    Tao Xiaohua
    Li Yumei
    Zhang Chunlei
    Li Linfeng
    Lu Jianyun
    Diao Qingchun
    Lu Qianjin
    Man Xiaoyong
    Li Fuqiu
    Xia Xiujuan
    Cheng Hao
    Jia Yingmin
    Zhao Guoqing
    Yan Jinchun
    Chen Bo
    中华医学杂志英文版, 2024, 137 (02)
  • [23] Tralokinumab Efficacy Over 1 Year in Adults with Moderate-to-Severe Atopic Dermatitis: Pooled Data from Two Phase III Trials
    Eric L. Simpson
    Andrew E. Pink
    Andrew Blauvelt
    Melinda Gooderham
    April W. Armstrong
    Margitta Worm
    Norito Katoh
    Ketty Peris
    Luis Puig
    Sébastien Barbarot
    Thomas Mark
    Louise Abildgaard Steffensen
    Ann-Marie Tindberg
    Andreas Wollenberg
    American Journal of Clinical Dermatology, 2023, 24 : 939 - 952
  • [24] Efficacy and safety of nemolizumab in paediatric patients aged 6-12 years with atopic dermatitis with moderate-to-severe pruritus: results from a phase III, randomized, double-blind, placebo-controlled, multicentre study
    Igarashi, Atsuyuki
    Katsunuma, Toshio
    Matsumura, Takayo
    Komazaki, Hiroshi
    BRITISH JOURNAL OF DERMATOLOGY, 2023, 190 (01) : 20 - 28
  • [25] Efficacy and Safety of Lebrikizumab in moderate to severe atopic Dermatitis: Results of two randomized, double-blind, placebo-controlled phase III Studies (ADvocate1 and ADvocate2) at 52 Weeks
    Blauvelt, A.
    Thyssen, J. P.
    Guttman-Yassky, E.
    Bieber, T.
    Serra-Baldrich, E.
    Simspon, E.
    Rosmarin, D.
    Diemert, S.
    Elmaraghy, H.
    Silverberg, J.
    ALLERGOLOGIE, 2023, 46 (08) : 530 - 530
  • [26] Tralokinumab Efficacy Over 1 Year in Adults with Moderate-to-Severe Atopic Dermatitis: Pooled Data from Two Phase III Trials
    Simpson, Eric L.
    Pink, Andrew E.
    Blauvelt, Andrew
    Gooderham, Melinda
    Armstrong, April W.
    Worm, Margitta
    Katoh, Norito
    Peris, Ketty
    Puig, Luis
    Barbarot, Sebastien
    Mark, Thomas
    Steffensen, Louise Abildgaard
    Tindberg, Ann-Marie
    Wollenberg, Andreas
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2023, 24 (06) : 939 - 952
  • [27] Safety and efficacy of upadacitinib monotherapy in adolescents and adults with moderate-to-severe atopic dermatitis: results from two pivotal, phase III, randomized, double-blinded, monotherapy, placebo-controlled studies (Measure Up 1 and Measure Up 2)
    Guttman-Yassky, E.
    Teixeira, H. D.
    Simpson, E. L.
    Papp, K. A.
    Pangan, A. L.
    Blauvelt, A.
    Thaci, D.
    Chu, C. Y.
    Hong, H. C.
    Katoh, N.
    Paller, A. S.
    Calimlim, B.
    Gu, Y.
    Hu, X.
    Liu, M.
    Yang, Y.
    Tenorio, A. R.
    Chu, A. D.
    Irvine, A. D.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 184 (03) : E62 - E62
  • [28] Tralokinumab significantly reduces Staphylococcus aureus colonization in adult patients with moderate-to-severe atopic dermatitis (AD): Results from a Phase 2b, randomized, double-blind, placebo-controlled study (NCT02347176)
    Guttman-Yassky, E.
    Silverberg, J. I.
    Fensholdt, J.
    Lindegaard, K. K.
    Wollenberg, A.
    EXPERIMENTAL DERMATOLOGY, 2018, 27 : 41 - 41
  • [29] Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis:: a randomized, double-blind, placebo-controlled trial
    Berth-Jones, J.
    Arkwright, P. D.
    Marasovic, D.
    Savani, N.
    Aldridge, C. R.
    Leech, S. N.
    Morgan, C.
    Clark, S. M.
    Ogilvie, S.
    Chopra, S.
    Harper, J. I.
    Smith, C. H.
    Rook, G. A. W.
    Friedmann, P. S.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2006, 36 (09): : 1115 - 1121
  • [30] Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis: results from the pivotal phase III, randomized, double-blind, placebo-controlled AD Up study
    Reich, K.
    Teixeira, H. D.
    De Bruin-Weller, M.
    Bieber, T.
    Soong, W.
    Kabashima, K.
    Werfel, T.
    Zeng, J.
    Huang, X.
    Hu, X.
    Ladizinski, B.
    Chu, A. D.
    Silverberg, J. I.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 184 (03) : E59 - E60
12345