2-[(3,5-Diamino-1H-pyrazol-4-yl)methylidene]-1,2-dihydro-3H-indol-3-ones: synthesis and properties

被引：2
|
作者：
Masterova, N. S. [1 ]
Ryabova, S. Yu. [1 ]
Alekseeva, L. M. [1 ]
Shashkov, A. S. [2 ]
Chernyshev, V. V. [3 ]
Granik, V. G. [1 ]
机构：
[1] State Res Ctr Antibiot, Moscow 117003, Russia
[2] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia
[3] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119899, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2009年 / 58卷 / 09期
关键词：
3-acetoxy-2-(2,2-dicyanovinyl)indole; hydrazines; 2-[(3,5-diamino-1H-pyrazol-4-yl)methylidene]indolin-3-ones; acetylation; X-ray diffraction analysis; DMF and DMAA dimethyl acetals; cyclization; pyrazolo[4 ',3 ':5,6]pyrido[3,2-b]indole; POWDER DIFFRACTION; DERIVATIVES; RELIABILITY; PYRIMIDINE; CRITERION; NITRILES; PROGRAM;
D O I：
10.1007/s11172-009-0269-y
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reactions of 3-acetoxy-2-(2,2-dicyanovinyl)indole with hydrazine hydrate and methyl-and phenylhydrazines afforded new indolin-3-one derivatives, namely, 2-[( 3,5-diaminopyrazol-4-yl)methylidene]indolin-3-ones. Reactions of the compounds obtained with acetic anhydride and DMF and DMAA dimethyl acetals were studied. Cyclization of 2-[(3,5-diamino-1H-pyrazol-4-yl)methylidene]-1,2-dihydro-3H-indolinone gave 3-amino-1,5-dihydropyrazolo-[4',3' : 5,6]pyrido[3,2-b]indole, a representative of a novel heterocyclic system.
引用
收藏
页码：1973 / 1980
页数：8
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