Theranostic biomaterials for tissue engineering

被引:10
|
作者
Kharbikar, Bhushan N. [1 ]
Zhong, Justin X. [1 ,2 ]
Cuylear, Darnell L. [1 ,3 ]
Perez, Cynthia A. [1 ,2 ,4 ]
Desai, Tejal A. [1 ,2 ,3 ,4 ]
机构
[1] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA
[2] Univ Calif Berkeley, UCSF Grad Program Bioengn, San Francisco, CA 94720 USA
[3] Univ Calif San Francisco, Sch Dent, Grad Program Oral & Craniofacial Sci, San Francisco, CA 94143 USA
[4] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Tissue engineering; Theranostics; Biomaterials; Nanoparticles; Scaf-folds; Cell-based devices; NANOPARTICLES; DELIVERY; TECHNOLOGIES; PARTICLES; CONTRAST; THERAPY; OXIDE;
D O I
10.1016/j.cobme.2021.100299
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Tissue engineering strategies, notably biomaterials, can be modularly designed and tuned to match specific patient needs. Although many challenges within tissue engineering remain, the incorporation of diagnostic strategies to create theranostic (combined therapy and diagnostic) biomaterials presents a unique platform to provide dual monitoring and treatment capabilities and advance the field toward personalized technologies. In this review, we summarize recent developments in this young field of regenerative theranostics and discuss the clinical potential and outlook of these systems from a tissue engineering perspective. As the need for precision and personalized medicines continues to increase to address diseases in all tissues in a patient-specific manner, we envision that such theranostic platforms can serve these needs.
引用
收藏
页数:9
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