PSMA PET-CT in the Diagnosis and Staging of Prostate Cancer

被引:51
作者
Combes, Alexander D. [1 ]
Palma, Catalina A. [1 ]
Calopedos, Ross [1 ]
Wen, Lingfeng [2 ,3 ]
Woo, Henry [4 ,5 ]
Fulham, Michael [2 ,4 ]
Leslie, Scott [1 ,4 ,5 ,6 ]
机构
[1] Royal Prince Alfred Hosp, Dept Urol, Sydney, NSW 2050, Australia
[2] Royal Prince Alfred Hosp, Dept Mol Imaging, Sydney, NSW 2050, Australia
[3] Univ Sydney, Fac Engn & Comp Sci, Sydney, NSW 2006, Australia
[4] Univ Sydney, Fac Med, Sydney, NSW 2006, Australia
[5] Chris Obrien Lifehouse, Dept Urol, Sydney, NSW 2050, Australia
[6] RPA Inst Acad Surg, Sydney, NSW 2050, Australia
关键词
prostate cancer; imaging; PSMA PET; LYMPH-NODE DISSECTION; POSITRON-EMISSION-TOMOGRAPHY; MEMBRANE ANTIGEN-EXPRESSION; RADICAL PROSTATECTOMY; BIOCHEMICAL RECURRENCE; PRECLINICAL EVALUATION; DUCTAL ADENOCARCINOMA; COMPUTED-TOMOGRAPHY; METASTATIC-DISEASE; GA-68-PSMA PET/CT;
D O I
10.3390/diagnostics12112594
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Prostate cancer is the most common cancer and the second leading cause of cancer death in men. The imaging assessment and treatment of prostate cancer has vastly improved over the past decade. The introduction of PSMA PET-CT has improved the detection of loco-regional and metastatic disease. PSMA PET-CT also has a role in the primary diagnosis and staging, in detecting biochemical recurrence after curative treatment and in metastasis-directed therapy. In this paper we review the role of PSMA PET-CT in prostate cancer.
引用
收藏
页数:25
相关论文
共 135 条
  • [1] PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions
    Afshar-Oromieh, A.
    Malcher, A.
    Eder, M.
    Eisenhut, M.
    Linhart, H. G.
    Hadaschik, B. A.
    Holland-Letz, T.
    Giesel, F. L.
    Kratochwil, C.
    Haufe, S.
    Haberkorn, U.
    Zechmann, C. M.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 (04) : 486 - 495
  • [2] Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients
    Afshar-Oromieh, Ali
    Holland-Letz, Tim
    Giesel, Frederik L.
    Kratochwil, Clemens
    Mier, Walter
    Haufe, Sabine
    Debus, Nils
    Eder, Matthias
    Eisenhut, Michael
    Schaefer, Martin
    Neels, Oliver
    Hohenfellner, Markus
    Kopka, Klaus
    Kauczor, Hans-Ulrich
    Debus, Juergen
    Haberkorn, Uwe
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 (08) : 1258 - 1268
  • [3] Radiation dosimetry of 68Ga-PSMA-11 (HBED-CC) and preliminary evaluation of optimal imaging timing
    Afshar-Oromieh, Ali
    Hetzheim, Henrik
    Kuebler, Wolfgang
    Kratochwil, Clemens
    Giesel, Frederik L.
    Hope, Thomas A.
    Eder, Matthias
    Eisenhut, Michael
    Kopka, Klaus
    Haberkorn, Uwe
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 (09) : 1611 - 1620
  • [4] The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer
    Afshar-Oromieh, Ali
    Avtzi, Eleni
    Giesel, Frederik L.
    Holland-Letz, Tim
    Linhart, Heinz G.
    Eder, Matthias
    Eisenhut, Michael
    Boxler, Silvan
    Hadaschik, Boris A.
    Kratochwil, Clemens
    Weichert, Wilko
    Kopka, Klaus
    Debus, Juergen
    Haberkorn, Uwe
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 (02) : 197 - 209
  • [5] Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study
    Ahmed, Hashim U.
    Bosaily, Ahmed El-Shater
    Brown, Louise C.
    Gabe, Rhian
    Kaplan, Richard
    Parmar, Mahesh K.
    Collaco-Moraes, Yolanda
    Ward, Katie
    Hindley, Richard G.
    Freeman, Alex
    Kirkham, Alex P.
    Oldroyd, Robert
    Parker, Chris
    Emberton, Mark
    [J]. LANCET, 2017, 389 (10071) : 815 - 822
  • [6] AJCC TNM Staging, US
  • [7] Mortality Results from a Randomized Prostate-Cancer Screening Trial
    Andriole, Gerald L.
    Grubb, Robert L., III
    Buys, Saundra S.
    Chia, David
    Church, Timothy R.
    Fouad, Mona N.
    Gelmann, Edward P.
    Kvale, Paul A.
    Reding, Douglas J.
    Weissfeld, Joel L.
    Yokochi, Lance A.
    Crawford, E. David
    O'Brien, Barbara
    Clapp, Jonathan D.
    Rathmell, Joshua M.
    Riley, Thomas L.
    Hayes, Richard B.
    Kramer, Barnett S.
    Izmirlian, Grant
    Miller, Anthony B.
    Pinsky, Paul F.
    Prorok, Philip C.
    Gohagan, John K.
    Berg, Christine D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (13) : 1310 - 1319
  • [8] [Anonymous], 2016, Guidelines for preventive activities in general practice, V9th
  • [9] PSMA Uptake in Mediastinal Sarcoidosis
    Ardies, Philip Junior
    Gykiere, Pieterjan
    Goethals, Lode
    De Mey, Johan
    De Geeter, Frank
    Everaert, Hendrik
    [J]. CLINICAL NUCLEAR MEDICINE, 2017, 42 (04) : 303 - 305
  • [10] Armstrong W, 2020, J NUCL MED, V61