Future prospect of "Gut microbiome composition can predict the response to nivolumab in advanced hepatocellular carcinoma patients"

被引：0
|
作者：
Kang, Yong-Bo [1 ]
Cai, Yue [1 ]
机构：
[1] Shanxi Med Univ, Dept Microbiol & Immunol, Sch Basic Med Sci, Wenhua St, Jinzhong 030600, Shanxi, Peoples R China
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2022年 / 28卷 / 20期
关键词：
Gut microbiome; Immunotherapy; Immune checkpoint inhibitor resistance; Probiotics; Faecal microbiota transplantation; Hepatocellular carcinoma; Prognosis;
D O I：
10.3748/wjg.v28.i20.2248
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Recently, we read the article "Gut microbiome composition can predict the response to nivolumab in advanced hepatocellular carcinoma patients" with interest, and it is preliminary suggested that gut microbiota is closely related to therapeutic effect of nivolumab. Based on the meaningful results of this article, several valuable research directions are proposed to enhance the therapeutic effect of immune checkpoint inhibitors on advanced hepatocellular carcinoma.
引用
收藏
页码：2248 / 2250
页数：3
相关论文
共 50 条
  • [31] Gut Microbiome Components Predict Response to Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer: A Prospective, Longitudinal Study
    Yi, Yuxi
    Shen, Lijun
    Shi, Wei
    Xia, Fan
    Zhang, Hui
    Wang, Yan
    Zhang, Jing
    Wang, Yaqi
    Sun, Xiaoyang
    Zhang, Zhiyuan
    Zou, Wei
    Yang, Wang
    Zhang, Lingyi
    Zhu, Ji
    Goel, Ajay
    Ma, Yanlei
    Zhang, Zhen
    CLINICAL CANCER RESEARCH, 2021, 27 (05) : 1329 - 1340
  • [32] Tissue and Imaging Biomarkers of Response to Neoadjuvant Nivolumab or Nivolumab plus Ipilimumab in Patients with Resectable Hepatocellular Carcinoma
    LaPelusa, Michael
    Chamseddine, Shadi
    Cao, Hop Sanderson Tran
    Xiao, Lianchun
    Hasanov, Elshad
    Bhosale, Priya
    Amin, Hesham M.
    Mohamed, Yehia I.
    Gok Yavuz, Betul
    Sakr, Yara
    Xu, Li
    Hu, Ian
    Lee, Sunyoung S.
    Sakamuri, Divya
    Jindal, Sonali
    Nguyen, Van
    Curran, Michael A.
    Sun, Ryan
    Rashid, Asif
    Duda, Dan Gabriel
    Sharma, Padmanee
    Qayyum, Aliya
    Kaseb, Ahmed Omar
    ONCOLOGY, 2024,
  • [33] Exposure-response analysis for nivolumab plus ipilimumab combination therapy in patients with advanced hepatocellular carcinoma (CheckMate 040)
    Sangro, Bruno
    Yau, Thomas
    El-Khoueiry, Anthony B.
    Kudo, Masatoshi
    Shen, Yun
    Tschaika, Marina
    Roy, Amit
    Feng, Yan
    Gao, Ling
    Aras, Urvi
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2023, 16 (08): : 1445 - 1457
  • [34] Nivolumab (Nivo) in Patients (Pts) With Advanced Hepatocellular Carcinoma (HCC): the CheckMate 040 Study
    Melero, Ignacio
    Sangro, Bruno
    Yau, Thomas
    Hsu, Chiun
    Kudo, Masatoshi
    Crocenzi, Todd S.
    Kim, Tae-You
    Choo, Su-pin
    Trojan, Jorg
    Meyer, Timothy
    Welling, Theodore
    Yeo, Winnie
    Chopra, Akhil
    Anderson, Jeffrey
    Delacruz, Christine
    Lang, Lixin
    Neely, Jaclyn
    Tang, Hao
    El-Khoueiry, Anthony B.
    HEPATOLOGY, 2016, 64 (06) : 1124A - 1124A
  • [35] A model to estimate survival in ambulatory patients with hepatocellular carcinoma: Can it predict the natural course of hepatocellular carcinoma?
    Choi, Won-Mook
    Yu, Su Jong
    Ahn, Hongkeun
    Cho, Hyeki
    Cho, Young Youn
    Lee, Minjong
    Yoo, Jeong-Ju
    Cho, Yuri
    Lee, Dong Hyeon
    Cho, Eun Ju
    Lee, Jeong-Hoon
    Kim, Yoon Jun
    Yoon, Jung-Hwan
    DIGESTIVE AND LIVER DISEASE, 2017, 49 (11) : 1273 - 1279
  • [36] A Model to Estimate Survival in Ambulatory Patients with Hepatocellular Carcinoma: Can It Predict the Natural Course of Hepatocellular Carcinoma?
    Choi, Won-Mook
    Yu, Su Jong
    Cho, Young Youn
    Cho, Eun Ju
    Lee, Jeong-Hoon
    Kim, Yoon Jun
    Yoon, Jung-Hwan
    Lee, June Sung
    HEPATOLOGY, 2015, 62 : 1138A - 1139A
  • [37] Sorafenib versus nivolumab after lenvatinib treatment failure in patients with advanced hepatocellular carcinoma
    Kim, Yuna
    Lee, Jae Seung
    Lee, Hye Won
    Kim, Beom Kyung
    Park, Jun Yong
    Kim, Do Young
    Ahn, Sang Hoon
    Goh, Myung Ji
    Kang, Wonseok
    Kim, Seung Up
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2023, 35 (02) : 191 - 197
  • [38] Real-world data on nivolumab treatment in Asian patients with advanced hepatocellular carcinoma
    Yoon, S. E.
    Hur, J. Y.
    Lee, K. K.
    Lee, S. J.
    Lee, J.
    Paik, S. W.
    Lim, H. Y.
    ANNALS OF ONCOLOGY, 2018, 29
  • [39] A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma
    Pinero, Federico
    Vazquez, Martin
    Bare, Patricia
    Rohr, Cristian
    Mendizabal, Manuel
    Sciara, Mariela
    Alonso, Cristina
    Fay, Fabian
    Silva, Marcelo
    ANNALS OF HEPATOLOGY, 2019, 18 (03) : 480 - 487
  • [40] Radiomics can predict tumour response in patients treated with Nivolumab for a metastatic renal cell carcinoma: an artificial intelligence concept
    Zine‐Eddine Khene
    Romain Mathieu
    Benoit Peyronnet
    Romain Kokorian
    Anis Gasmi
    Fares Khene
    Nathalie Rioux-Leclercq
    Solène-Florence Kammerer-Jacquet
    Shahrokh Shariat
    Brigitte Laguerre
    Karim Bensalah
    World Journal of Urology, 2021, 39 : 3707 - 3709
12345