Hallucinations and antipsychotics: The role of the 5-HT2A receptor

被引：0
|
作者：
Goudie, AJ [1 ]
Cole, JC [1 ]
机构：
[1] Univ Liverpool, Sch Psychol, Liverpool L69 7ZA, Merseyside, England
来源：
BEHAVIORAL AND BRAIN SCIENCES | 2004年 / 27卷 / 06期
关键词：
D O I：
10.1017/S0140525X0430018X
中图分类号：
B84 [心理学];
学科分类号：
04 ; 0402 ;
摘要：
Behrendt & Young's (B&Y's) novel "unifying model" of hallucinations, although comprehensive, fails to incorporate research into the possible role of 5-HT2A receptors in the mode of action of novel "atypical" antipsychotic drugs (which treat hallucinations effectively), and into the role of such receptors, which are located in thalamocortical circuits, in mediating drug-induced hallucinations.
引用
收藏
页码：795 / +
页数：14
相关论文
共 50 条
  • [41] Dual role of 5-HT2A receptor and 5-HT transporter in norfenfluramine-induced aortic contraction
    Ni, W
    Li, MW
    Watts, SW
    FASEB JOURNAL, 2004, 18 (04): : A283 - A283
  • [42] PRIMARY STRUCTURE OF THE HUMAN PLATELET SEROTONIN 5-HT2A RECEPTOR - IDENTITY WITH FRONTAL-CORTEX SEROTONIN 5-HT2A RECEPTOR
    COOK, EH
    FLETCHER, KE
    WAINWRIGHT, M
    MARKS, N
    YAN, SY
    LEVENTHAL, BL
    JOURNAL OF NEUROCHEMISTRY, 1994, 63 (02) : 465 - 469
  • [43] A case of ziprasidone-induced mania and the role of 5-HT2A in mood changes induced by atypical antipsychotics
    Lu, BY
    Lundgren, R
    Escalona, PR
    Roberts, BB
    JOURNAL OF CLINICAL PSYCHIATRY, 2002, 63 (12) : 1185 - 1186
  • [44] Different effects of the 5-HT2A receptor agonist DOI and the 5-HT2A receptor antagonist altanserin on D2 receptor binding in the rat brain
    Nikolaus, S.
    Wittsack, H.
    Beu, M.
    Antke, C.
    Hautzel, H.
    Mori, Y.
    Mamlins, E.
    Antoch, G.
    Mueller, H.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (SUPPL 1) : S635 - S635
  • [45] Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin
    Holze, Friederike
    Avedisian, Isidora
    Varghese, Nimmy
    Eckert, Anne
    Liechti, Matthias E. E.
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [46] Role of the 5-HT2A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice
    Halberstadt, Adam L.
    Powell, Susan B.
    Geyer, Mark A.
    NEUROPHARMACOLOGY, 2013, 70 : 218 - 227
  • [47] Serotonin Receptor Activity Profiles (5-HT2B and 5-HT2A) for Nine Commercialized Ergot Alkaloids Correspond to Known Risks of Fibrosis and Hallucinations
    Alam, A.
    Alam, A.
    HEADACHE, 2019, 59 : 135 - 136
  • [48] THE ROLE OF 5-HT2A RECEPTORS IN ANTIPSYCHOTIC ACTIVITY
    SCHMIDT, CJ
    SORENSEN, SM
    KEHNE, JH
    CARR, AA
    PALFREYMAN, MG
    LIFE SCIENCES, 1995, 56 (25) : 2209 - 2222
  • [49] Different effects of 5-HT2A and 5-HT2C receptor stimulation on cortical dopamine (DA) release in 5-HT2A knockout mice
    Huang, M.
    Li, Z.
    Prus, A. J.
    Gardell, L.
    Bonhaus, D.
    Dai, J.
    Meltzer, H. Y.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S221 - S221
  • [50] Mining the (5-HT) 5-HT2A Receptor (5-HT2AR) and 5-HT2CR Complex
    Cunningham, Kathryn
    Allen, John
    Elferink, Lisa A.
    Gilbertson, Scott R.
    Moeller, F. Gerard
    Anastasio, Noelle C.
    NEUROPSYCHOPHARMACOLOGY, 2016, 41 : S611 - S611
12345