Hallucinations and antipsychotics: The role of the 5-HT2A receptor

被引:0
|
作者
Goudie, AJ [1 ]
Cole, JC [1 ]
机构
[1] Univ Liverpool, Sch Psychol, Liverpool L69 7ZA, Merseyside, England
关键词
D O I
10.1017/S0140525X0430018X
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Behrendt & Young's (B&Y's) novel "unifying model" of hallucinations, although comprehensive, fails to incorporate research into the possible role of 5-HT2A receptors in the mode of action of novel "atypical" antipsychotic drugs (which treat hallucinations effectively), and into the role of such receptors, which are located in thalamocortical circuits, in mediating drug-induced hallucinations.
引用
收藏
页码:795 / +
页数:14
相关论文
共 50 条
  • [1] The role of 5-HT2A receptor and 5-HT2A/5-HT1A receptor interaction in the suppression of catalepsy
    Naumenko, V. S.
    Bazovkina, D. V.
    Kondaurova, E. M.
    Zubkov, E. A.
    Kulikov, A. V.
    GENES BRAIN AND BEHAVIOR, 2010, 9 (05) : 519 - 524
  • [2] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
    Kimura, Kanako Terakado
    Asada, Hidetsugu
    Inoue, Asuka
    Kadji, Francois Marie Ngako
    Im, Dohyun
    Mori, Chihiro
    Arakawa, Takatoshi
    Hirata, Kunio
    Nomura, Yayoi
    Nomura, Norimichi
    Aoki, Junken
    Iwata, So
    Shimamura, Tatsuro
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2019, 26 (02) : 121 - +
  • [3] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
    Kanako Terakado Kimura
    Hidetsugu Asada
    Asuka Inoue
    Francois Marie Ngako Kadji
    Dohyun Im
    Chihiro Mori
    Takatoshi Arakawa
    Kunio Hirata
    Yayoi Nomura
    Norimichi Nomura
    Junken Aoki
    So Iwata
    Tatsuro Shimamura
    Nature Structural & Molecular Biology, 2019, 26 : 121 - 128
  • [4] Role of the serotonin 5-HT2A receptor in learning
    Harvey, JA
    LEARNING & MEMORY, 2003, 10 (05) : 355 - 362
  • [5] The relationship between the cognitive phenotype and 5-HT2A receptor in PD with visual hallucinations
    Cho, S. S.
    Strafella, A. P.
    Duff-Canning, S.
    Zurowski, M.
    Vijverman, A. -C.
    Bruno, V.
    de Aquino, C.
    Criaud, M.
    Rusjan, P. M.
    Houle, S.
    Fox, S. H.
    MOVEMENT DISORDERS, 2016, 31 : S89 - S89
  • [6] Role of the 5-HT2A receptor in associative learning.
    Harvey, JA
    JOURNAL OF NEUROCHEMISTRY, 1998, 71 : S59 - S59
  • [7] Neurophysiological studies of psilocybin-induced hallucinations: role of 5-HT2A receptors
    Vollenweider, F. X.
    Schmidt, A.
    Kometer, M.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2012, 15 : 23 - 24
  • [8] Role of 5-HT2A receptor antagonists in the treatment of insomnia
    Vanover, Kimberly E.
    Davis, Robert E.
    NATURE AND SCIENCE OF SLEEP, 2010, 2 : 139 - 150
  • [9] The role of the 5-HT2A receptor gene in psychosis.
    Sodhi, MS
    Aitchison, KJ
    Kerwin, RW
    Sham, P
    AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (04) : A469 - A469
  • [10] 5-HT2A Receptor Signaling
    Panicker, M. M.
    JOURNAL OF NEUROCHEMISTRY, 2013, 125 : 25 - 25