Sweet secrets of synthesis

被引：40

作者：

Davies, GJ ^{[1
]}

机构：

[1] Univ York, Dept Chem, Struct Biol Lab, York YO10 5DD, N Yorkshire, England

来源：

NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 02期

关键词：

D O I：

10.1038/84198

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structure of a 'retaining' glycosyltransferase provides the first view of cc-glycosidic bond synthesis using activated nucleotide sugars.

引用

页码：98 / 100

页数：3

共 21 条

[11] Heparan/chondroitin sulfate biosynthesis - Structure and mechanism of human glucuronyltransferase I [J].

Pedersen, LC ;

Tsuchida, K ;

Kitagawa, H ;

Sugahara, K ;

Darden, TA ;

Negishi, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (44) :34580-34585

[12] Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs [J].

Persson, K ;

Ly, HD ;

Dieckelmann, M ;

Wakarchuk, WW ;

Withers, SG ;

Strynadka, NCJ .

NATURE STRUCTURAL BIOLOGY, 2001, 8 (02) :166-175

[13] Intervention of carbohydrate recognition by proteins and nucleic acids [J].

Sears, P ;

Wong, CH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (22) :12086-12093

[14] CATALYTIC MECHANISMS OF ENZYMATIC GLYCOSYL TRANSFER [J].

SINNOTT, ML .

CHEMICAL REVIEWS, 1990, 90 (07) :1171-1202

[15] X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family [J].

Uitdehaag, JCM ;

Mosi, R ;

Kalk, KH ;

van der Veen, BA ;

Dijkhuizen, L ;

Withers, SG ;

Dijkstra, BW .

NATURE STRUCTURAL BIOLOGY, 1999, 6 (05) :432-436

[16] X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I:: catalytic mechanism and a new protein superfamily [J].

Ünligil, UM ;

Zhou, SH ;

Yuwaraj, S ;

Sarkar, M ;

Schachter, H ;

Rini, JM .

EMBO JOURNAL, 2000, 19 (20) :5269-5280

[17] Glycosyltransferase structure and mechanism [J].

Ünligil, UM ;

Rini, JM .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2000, 10 (05) :510-517

[18] CRYSTAL-STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE [J].

VRIELINK, A ;

RUGER, W ;

DRIESSEN, HPC ;

FREEMONT, PS .

EMBO JOURNAL, 1994, 13 (15) :3413-3422

[19] Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question [J].

Watson, KA ;

McCleverty, C ;

Geremia, S ;

Cottaz, S ;

Driguez, H ;

Johnson, LN .

EMBO JOURNAL, 1999, 18 (17) :4619-4632

[20] Crystallographic observation of a covalent catalytic intermediate in a beta-glycosidase [J].

White, A ;

Tull, D ;

Johns, K ;

Withers, SG ;

Rose, DR .

NATURE STRUCTURAL BIOLOGY, 1996, 3 (02) :149-154

← 1 2 3 →