Heterocycles LXXVIII.: Electrophilic substitution of 2′-phenyl-4R-2,4′-bisthiazoles

被引:7
|
作者
Oniga, O
Grosu, I
Mager, S
Simiti, I [1 ]
机构
[1] Univ Med & Pharm Iuliu Hatieganu, Dept Organ Chem, Fac Pharm, RO-3400 Cluj Napoca, Romania
[2] Univ Babes Bolyai, Dept Organ Chem, RO-3400 Cluj Napoca, Romania
来源
MONATSHEFTE FUR CHEMIE | 1998年 / 129卷 / 6-7期
关键词
atropisomerism; 2,4 '-bisthiazoles; halogenation; nitration;
D O I
10.1007/PL00013474
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The behaviour of some 2/-phenyl-4R-2,4'-bisthiazoles with respect to electrophilic substitution reactions (halogenation and nitration) has been studied in order to establish relationships between structure and reactivity of the two thiazole rings. The entry of the electrophilic reactants in position 5 or 5' of the 2,4'-bisthiazole system depends on the nature of the residue in position 4.
引用
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页码:661 / 669
页数:9
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