Maternal Influences over Offspring Allergic Responses

被引：28

作者：

Cook-Mills, Joan M. ^{[1
]}

机构：

[1] Northwestern Univ, Div Allergy Immunol, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

CURRENT ALLERGY AND ASTHMA REPORTS | 2015年 / 15卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Allergy; Neonate; Fetus; Dendritic cells; Corticosterone; alpha-Tocopherol; TOCOPHEROL TRANSFER PROTEIN; OVA-SENSITIZED RATS; VITAMIN-E; ALPHA-TOCOPHEROL; ASTHMA RISK; T-CELLS; GAMMA-TOCOPHEROL; BREAST-MILK; DENDRITIC CELLS; MURINE MODEL;

D O I：

10.1007/s11882-014-0501-1

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Asthma occurs as a result of complex interactions of environmental and genetic factors. Clinical studies and animal models of asthma indicate offspring of allergic mothers have increased risk of development of allergies. Environmental factors including stress-induced corticosterone and vitamin E isoforms during pregnancy regulate the risk for offspring development of allergy. In this review, we discuss mechanisms for the development of allergic disease early in life, environmental factors that may impact the development of risk for allergic disease early in life, and how the variation in global prevalence of asthma may be explained, at least in part, by some environmental components.

引用

页数：10

共 113 条

[1] α-Tocopherol supplementation of allergic female mice inhibits development of CD11c+CD11b+ dendritic cells in utero and allergic inflammation in neonates [J].

Abdala-Valencia, Hiam ;

Berdnikovs, Sergejs ;

Soveg, Frank W. ;

Cook-Mills, Joan M. .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2014, 307 (06) :L482-L496

[2]

Allan K. M., 2014, EUR RESPIR J, V30

[3] Parental allergic status influences the risk of developing allergic sensitization and an asthmatic-like phenotype in canine offspring [J].

Barrett, EG ;

Rudolph, K ;

Bowen, LE ;

Bice, DE .

IMMUNOLOGY, 2003, 110 (04) :493-500

[4] The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing [J].

Beigelman, Avraham ;

Zeiger, Robert S. ;

Mauger, David ;

Strunk, Robert C. ;

Jackson, Daniel J. ;

Martinez, Fernando D. ;

Morgan, Wayne J. ;

Covar, Ronina ;

Szefler, Stanley J. ;

Taussig, Lynn M. ;

Bacharier, Leonard B. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (05) :1489-+

[5] Isoforms of Vitamin E Have Opposing Immunoregulatory Functions during Inflammation by Regulating Leukocyte Recruitment [J].

Berdnikovs, Sergejs ;

Abdala-Valencia, Hiam ;

McCary, Christine ;

Somand, Michelle ;

Cole, Rokeisha ;

Garcia, Alex ;

Bryce, Paul ;

Cook-Mills, Joan M. .

JOURNAL OF IMMUNOLOGY, 2009, 182 (07) :4395-4405

[6] Prenatal lipopolysaccharide-exposure prevents allergic sensitization and airway inflammation, but not airway responsiveness in a murine model of experimental asthma [J].

Blümer, N ;

Herz, U ;

Wegmann, M ;

Renz, H .

CLINICAL AND EXPERIMENTAL ALLERGY, 2005, 35 (03) :397-402

[7]

Bousquet J, 2005, B WORLD HEALTH ORGAN, V83, P548

[8] MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine [J].

Bousquet, J. ;

Anto, J. ;

Auffray, C. ;

Akdis, M. ;

Cambon-Thomsen, A. ;

Keil, T. ;

Haahtela, T. ;

Lambrecht, B. N. ;

Postma, D. S. ;

Sunyer, J. ;

Valenta, R. ;

Akdis, C. A. ;

Annesi-Maesano, I. ;

Arno, A. ;

Bachert, C. ;

Ballester, F. ;

Basagana, X. ;

Baumgartner, U. ;

Bindslev-Jensen, C. ;

Brunekreef, B. ;

Carlsen, K. H. ;

Chatzi, L. ;

Crameri, R. ;

Eveno, E. ;

Forastiere, F. ;

Garcia-Aymerich, J. ;

Guerra, S. ;

Hammad, H. ;

Heinrich, J. ;

Hirsch, D. ;

Jacquemin, B. ;

Kauffmann, F. ;

Kerkhof, M. ;

Kogevinas, M. ;

Koppelman, G. H. ;

Kowalski, M. L. ;

Lau, S. ;

Lodrup-Carlsen, K. C. ;

Lopez-Botet, M. ;

Lotvall, J. ;

Lupinek, C. ;

Maier, D. ;

Makela, M. J. ;

Martinez, F. D. ;

Mestres, J. ;

Momas, I. ;

Nawijn, M. C. ;

Neubauer, A. ;

Oddie, S. ;

Palkonen, S. .

ALLERGY, 2011, 66 (05) :596-604

[9] Cytokines of the placenta and extra-placental membranes: Biosynthesis, secretion and roles in establishment of pregnancy in women [J].

Bowen, JM ;

Chamley, L ;

Mitchell, MD ;

Keelan, JA .

PLACENTA, 2002, 23 (04) :239-256

[10] Red blood cell and tissue phospholipid fatty acid profiles of weanling rats fed infant formula fat blends containing soy and/or corn oil [J].

Boyle, FG ;

Yuhas, RJ ;

Lien, EL .

ANNALS OF NUTRITION AND METABOLISM, 1996, 40 (04) :234-242

← 1 2 3 4 5 6 7 8 9 10 →