Systemic therapy in addition to cytoreduction and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: recent insights from clinical studies and translational research

被引：7
作者：
Bakkers, Checca [1 ]
Simkens, Geert A. A. M. [1 ]
De Hingh, Ignace H. J. T. [1 ,2 ]
机构：
[1] Catharina Canc Inst, Dept Surg, POB 1350, NL-5602 ZA Eindhoven, Netherlands
[2] Maastricht Univ, GROW Sch Oncol & Dev Biol, Maastricht, Netherlands
来源：
JOURNAL OF GASTROINTESTINAL ONCOLOGY | 2021年 / 12卷
关键词：
Systemic therapy; cytoreductive surgery (CRS); hyperthermic intraperitoneal chemotherapy (HIPEC); peritoneal metastases (PM); colorectal cancer; CONSENSUS MOLECULAR SUBTYPES; RESECTABLE LIVER METASTASES; COLON-CANCER; 1ST-LINE TREATMENT; RAS MUTATIONS; POSTOPERATIVE COMPLICATIONS; CURATIVE TREATMENT; RANDOMIZED-TRIAL; BRAF MUTATION; STAGE-II;
D O I：
10.21037/jgo-20-133
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
There is a lack of randomized or high-quality intention-to-treat cohort studies addressing the role of systemic therapy in addition to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) as part of the treatment of colorectal peritoneal metastases (PM). Therefore, the choice whether or not to treat patients with systemic therapy is currently mainly based on expert opinion. As a result, treatment with neoadjuvant and/or adjuvant systemic therapy is implemented in various ways around the world. The aim of this review was to provide an overview of recent insights with regard to the systemic treatment of PM of colorectal origin obtained from clinical studies and translational research.
引用
收藏
页码：S206 / S213
页数：8
相关论文
共 61 条
  • [1] American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy
    Allegra, Carmen J.
    Jessup, J. Milburn
    Somerfield, Mark R.
    Hamilton, Stanley R.
    Hammond, Elizabeth H.
    Hayes, Daniel F.
    McAllister, Pamela K.
    Morton, Roscoe F.
    Schilsky, Richard L.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (12) : 2091 - 2096
  • [2] Postoperative Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Affect Long-term Outcome of Patients With Peritoneal Metastases From Colorectal Cancer: a Two-Center Study of 101 Patients
    Baratti, D.
    Kusamura, S.
    Iusco, D.
    Bonomi, S.
    Grassi, A.
    Virzi, S.
    Leo, E.
    Deraco, M.
    [J]. DISEASES OF THE COLON & RECTUM, 2014, 57 (07) : 858 - 868
  • [3] Beyond Exon 2-The Developing Story of RAS Mutations in Colorectal Cancer
    Berlin, Jordan
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (11) : 1059 - 1060
  • [4] The current practice of cytoreductive surgery and HIPEC for colorectal peritoneal metastases: Results of a worldwide web-based survey of the Peritoneal Surface Oncology Group International (PSOGI)
    Bushati, M.
    Rovers, K. P.
    Sommariva, A.
    Sugarbaker, P. H.
    Morris, D. L.
    Yonemura, Y.
    Quadros, C. A.
    Somashekhar, S. P.
    Ceelen, W.
    Dube, P.
    Li, Y.
    Verwaal, V. J.
    Glehen, O.
    Piso, P.
    Spiliotis, J.
    Teo, M. C. C.
    Gonzalez-Moreno, S.
    Cashin, P. H.
    Lehmann, K.
    Deraco, M.
    Moran, B.
    de Hingh, I. H. J. T.
    [J]. EJSO, 2018, 44 (12): : 1942 - 1948
  • [5] Drug therapy: EGFR antagonists in cancer treatment
    Ciardiello, Fortunato
    Tortora, Giampaolo
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (11) : 1160 - 1174
  • [6] Cleeland Charles S, 2007, J Natl Cancer Inst Monogr, P16
  • [7] Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
    De Sousa E Melo, Felipe
    Wang, Xin
    Jansen, Marnix
    Fessler, Evelyn
    Trinh, Anne
    de Rooij, Laura P. M. H.
    de Jong, Joan H.
    de Boer, Onno J.
    van Leersum, Ronald
    Bijlsma, Maarten F.
    Rodermond, Hans
    van der Heijden, Maartje
    van Noesel, Carel J. M.
    Tuynman, Jurriaan B.
    Dekker, Evelien
    Markowetz, Florian
    Medema, Jan Paul
    Vermeulen, Louis
    [J]. NATURE MEDICINE, 2013, 19 (05) : 614 - 618
  • [8] Increased Survival of Patients with Synchronous Colorectal Peritoneal Metastases Receiving Preoperative Chemotherapy Before Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Devilee, R. A.
    Simkens, G. A.
    van Oudheusden, T. R.
    Rutten, H. J.
    Creemers, G. J.
    ten Tije, A. J.
    de Hingh, I. H.
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2016, 23 (09) : 2841 - 2848
  • [9] Panitumumab-FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer
    Douillard, Jean-Yves
    Oliner, Kelly S.
    Siena, Salvatore
    Tabernero, Josep
    Burkes, Ronald
    Barugel, Mario
    Humblet, Yves
    Bodoky, Gyorgy
    Cunningham, David
    Jassem, Jacek
    Rivera, Fernando
    Kocakova, Ilona
    Ruff, Paul
    Blasinska-Morawiec, Maria
    Smakal, Martin
    Canon, Jean Luc
    Rother, Mark
    Williams, Richard
    Rong, Alan
    Wiezorek, Jeffrey
    Sidhu, Roger
    Patterson, Scott D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (11) : 1023 - 1034
  • [10] Peritoneal Colorectal Carcinomatosis Treated With Surgery and Perioperative Intraperitoneal Chemotherapy: Retrospective Analysis of 523 Patients From a Multicentric French Study
    Elias, Dominique
    Gilly, Francois
    Boutitie, Florent
    Quenet, Francois
    Bereder, Jean-Marc
    Mansvelt, Baudouin
    Lorimier, Gerard
    Dube, Pierre
    Glehen, Olivier
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (01) : 63 - 68
1234567