Evaluation of influence of anisotropic diffusion near a wall in near-field fluorescence correlation spectroscopy of nanoparticles

被引:0
作者
Kasahara, Kazuo [1 ]
Saiki, Toshiharu [1 ]
机构
[1] Keio Univ, Grad Sch Sci & Technol, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
关键词
near-field optical microscopy; fluorescence correlation spectroscopy; hydrodynamics; diffusion coefficient; INTERFACES; FLUID;
D O I
10.1007/s10043-011-0048-5
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Fluorescence correlation spectroscopy (FCS) of colloidal nanoparticles using a near-field fiber probe was numerically simulated. The near-wall dynamics was simulated by accounting for the anisotropic mobility of nanoparticles owing to hydrodynamic interaction with a wall (Stokes viscous force). By comparing the simulation results with theoretical model calculations, we found that the influence of anisotropic diffusion is insignificant in near-field FCS autocorrelation analysis.
引用
收藏
页码:237 / 240
页数:4
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