The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction

被引：25

作者：

Dai, Chaofeng

Wang, Lifang

Sheng, Jia

Peng, Hanjing

Draganov, Alexander Boryanov

Huang, Zhen

Wang, Binghe ^{[1
]}

机构：

[1] Georgia State Univ, Dept Chem, Atlanta, GA 30302 USA

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 12期

基金：

美国国家卫生研究院;

关键词：

CYCLOADDITION REACTION; TERMINAL ALKYNES; CHEMISTRY; DESIGN; AZIDES;

D O I：

10.1039/c0cc04546b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

引用

页码：3598 / 3600

页数：3

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