A Rare Case of Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplant Patient

被引:14
|
作者
Sahu, Kamal Kant [1 ]
Prakash, Gaurav [1 ]
Khadwal, Alka [1 ]
Varma, Subhash Chander [1 ]
Malhotra, Pankaj [1 ]
机构
[1] Postgrad Inst Med Educ & Res, Dept Internal Med, Chandigarh 160012, India
关键词
BONE-MARROW-TRANSPLANTATION; ADENOVIRUS DISEASE; RIBAVIRIN THERAPY; RISK-FACTORS; INSTILLATION; RECIPIENTS; INFECTION; CHILDREN;
D O I
10.1007/s12288-015-0530-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Post bone marrow transplant patients are susceptible to atypical infections, especially viral pathogens. The risk increases many folds in cases of allogeneic transplantation, which also receive GVHD prophylaxis. Viral pathogens like cytomegalovirus and herpes are the common ones encountered during follow-up period. However, in recent times there have been reports of a variety of disease manifestations of rare viruses like polyoma virus and adenovirus. These viral infections may play a crucial role in morbidity and mortality in immunocompromised patients. We hereby elaborate the follow-up course of a 36-year-old post allogeneic transplant patient of acute myeloid leukemia who developed adenovirus related haemorrhagic cystitis. Treatment with oral ribavirin lead to dramatic improvement in symptomatology within a week. This cases re-emphasizes the fact that after ruling out the commoner pathogens, it's of utmost importance to strongly consider the atypical pathogens in such cases.
引用
收藏
页码:S196 / S200
页数:5
相关论文
共 50 条
  • [41] Presentation of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic cell transplantation
    Imlay, Hannah
    Xie, Hu
    Leisenring, Wendy M.
    Duke, Elizabeth R.
    Kimball, Louise E.
    Huang, Meei-Li
    Pergam, Steven A.
    Hill, Joshua A.
    Jerome, Keith R.
    Milano, Filippo
    Nichols, W. Garrett
    Pang, Phillip S.
    Hirsch, Hans H.
    Limaye, Ajit P.
    Boeckh, Michael
    BLOOD ADVANCES, 2020, 4 (04) : 617 - 628
  • [42] Allogeneic hematopoietic stem cell transplant in rare hematologic disorders: a single center experience from Pakistan
    Khan, Maryam
    Iftikhar, Raheel
    Ghafoor, Tariq
    Hussain, Fayyaz
    Chaudhry, Qamar un Nisa
    Mahmood, Syed Kamran
    Shahbaz, Nighat
    Khan, Mehreen Ali
    Khattak, Tariq Azam
    Shamshad, Ghassan Umair
    Rehman, Jahanzeb
    Ali, Sundas
    Shah, Zunaira
    Rafae, Abdul
    Farhan, Muhammad
    Anwer, Faiz
    Ahmed, Parvez
    BONE MARROW TRANSPLANTATION, 2021, 56 (04) : 863 - 872
  • [43] Hemorrhagic cystitis in pediatric severe aplastic anemia undergoing haploidentical hematopoietic stem cell transplantation: incidence, risk factors and outcomes
    Cui, Kai
    Zhang, Senlin
    Liang, Mingchu
    He, Chenchen
    Chen, Jie
    Wei, Yufeng
    Hu, Shaoyan
    Li, Jie
    BMC PEDIATRICS, 2025, 25 (01)
  • [44] Hemorrhagic cystitis after allogeneic hematopoietic cell transplantation: risk factors, graft source and survival
    Lunde, L. E.
    Dasaraju, S.
    Cao, Q.
    Cohn, C. S.
    Reding, M.
    Bejanyan, N.
    Trottier, B.
    Rogosheske, J.
    Brunstein, C.
    Warlick, E.
    Young, J. A. H.
    Weisdorf, D. J.
    Ustun, C.
    BONE MARROW TRANSPLANTATION, 2015, 50 (11) : 1432 - 1437
  • [45] A case of BK virus nephropathy without hemorrhagic cystitis after hematopoietic stem cell transplantation
    Burbach, Maren
    Birsen, Rudy
    Denis, Blandine
    Munier, Anne-Lise
    Verine, Jerome
    de Fontbrune, Flore Sicre
    Peraldi, Marie-Noelle
    ANNALS OF HEMATOLOGY, 2016, 95 (09) : 1567 - 1568
  • [46] Analysis of Hemorrhagic Cystitis and BK Viremia in Children after Hematopoietic Stem Cell Transplantation
    Yozgat, Ayca
    Bozkaya, Ikbal
    Aksu, Tekin
    Isik, Pamir
    Kanbur, Mehtap
    Tiryaki, Tugrul
    Yarali, Nese
    oezbek, Namik
    INDIAN JOURNAL OF TRANSPLANTATION, 2022, 16 (02) : 174 - 179
  • [47] Hemorrhagic Cystitis Requiring Bladder Irrigation is Associated with Poor Mortality in Hospitalized Stem Cell Transplant Patients
    Raup, Valary T.
    Potretzke, Aaron M.
    Manley, Brandon J.
    Brockman, John A.
    Bhayani, Sam B.
    INTERNATIONAL BRAZ J UROL, 2015, 41 (06): : 1126 - 1131
  • [48] Efficacy and Safety of Ciprofloxacin for Prophylaxis of Polyomavirus BK Virus-Associated Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
    Miller, Ashley N.
    Glode, Ashley
    Hogan, Kathy R.
    Schaub, Christine
    Kramer, Cindy
    Stuart, Robert K.
    Costa, Luciano J.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2011, 17 (08) : 1176 - 1181
  • [49] High incidence of BK virus-associated hemorrhagic cystitis in children after second or third allogeneic hematopoietic stem cell transplantation
    Umeda, Katsutsugu
    Kato, Itaru
    Kawaguchi, Koji
    Tasaka, Keiji
    Kamitori, Tatsuya
    Ogata, Hideto
    Mikami, Takashi
    Hiramatsu, Hidefumi
    Saito, Ryoichi
    Ogawa, Osamu
    Takahashi, Takayuki
    Adachi, Souichi
    PEDIATRIC TRANSPLANTATION, 2018, 22 (04)
  • [50] Immune Deficits in Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients
    Mir, Muhammad A.
    Battiwalla, Minoo
    MYCOPATHOLOGIA, 2009, 168 (06) : 271 - 282