Fluorescence Imaging of Azobenzene Photoswitching In Vivo

被引：128
作者：
Beharry, Andrew A. [1 ]
Wong, Loksum [2 ]
Tropepe, Vince [2 ]
Woolley, G. Andrew [1 ]
机构：
[1] Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada
[2] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON M5S 3G5, Canada
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 06期
基金：
加拿大自然科学与工程研究理事会;
关键词：
azobenzene; fluorescence; peptides; photo-control; photoisomerization; PHOTOCONTROL;
D O I：
10.1002/anie.201006506
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Switching zebrafish: A fluorescent reporter peptide permits imaging of azobenzene photoisomerization in vivo (see picture), which indicates that azobenzene-based photochemical switches may be generally useful for spatiotemporal control in living systems. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1325 / 1327
页数：3
相关论文
共 20 条
  • [1] [Anonymous], 2010, ANGEW CHEM-GER EDIT, DOI DOI 10.1002/ANGE.200907082
  • [2] Reversibility of conformational switching in light-sensitive peptides
    Borisenko, V
    Woolley, GA
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2005, 173 (01) : 21 - 28
  • [3] Redox potential of azobenzene as an amino acid residue in peptides
    Boulegue, Cyril
    Loeweneck, Markus
    Renner, Christian
    Moroder, Luis
    [J]. CHEMBIOCHEM, 2007, 8 (06) : 591 - 594
  • [4] Kusebauch U., 2006, ANGEW CHEM, V118, P7170, DOI DOI 10.1002/ANGE.200601432
  • [5] Photocontrolled folding and unfolding of a collagen triple helix
    Kusebauch, Ulrike
    Cadamuro, Sergio A.
    Musiol, Hans-Juergen
    Lenz, Martin O.
    Wachtveitl, Josef
    Moroder, Luis
    Renner, Christian
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (42) : 7015 - 7018
  • [6] METABOLISM OF AZO DYES - IMPLICATION FOR DETOXICATION AND ACTIVATION
    LEVINE, WG
    [J]. DRUG METABOLISM REVIEWS, 1991, 23 (3-4) : 253 - 309
  • [7] Photoregulation of DNA transcription by using photoresponsive T7 promoters and clarification of its mechanism
    Liang, Xingguo
    Wakuda, Ryuji
    Fujioka, Kenta
    Asanuma, Hiroyuki
    [J]. FEBS JOURNAL, 2010, 277 (06) : 1551 - 1561
  • [8] Azobenzene as conformational switch in model peptides
    Renner, Christian
    Moroder, Luis
    [J]. CHEMBIOCHEM, 2006, 7 (06) : 869 - 878
  • [9] Controlling the enzymatic activity of a restriction enzyme by light
    Schierling, Benno
    Noel, Ann-Josee
    Wende, Wolfgang
    Hien, Le Thi
    Volkov, Eugeny
    Kubareva, Elena
    Oretskaya, Tatiana
    Kokkinidis, Michael
    Roempp, Andreas
    Spengler, Bernhard
    Pingoud, Alfred
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (04) : 1361 - 1366
  • [10] Abc amino acids: Design, synthesis, and properties of new photoelastic amino acids
    Standaert, Robert F.
    Park, Seung Bum
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (21) : 7952 - 7966
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