TGF-β in Th17 Cell Development: The Truth Is Out There

被引：41
|
作者：
Hatton, Robin D. [1 ]
机构：
[1] Univ Alabama, Dept Pathol, Birmingham, AL 35294 USA
来源：
IMMUNITY | 2011年 / 34卷 / 03期
关键词：
T-CELLS; LINEAGE; DIFFERENTIATION; DISTINCT;
D O I：
10.1016/j.immuni.2011.03.009
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
As Th17 cell developmental requirements continue to be studied, Gutcher et al. (2011) demonstrate in this issue of Immunity that autocrine TGF-beta cytokine promotes Th17 cell development and maintenance.
引用
收藏
页码：288 / 290
页数：3
相关论文
共 50 条
  • [21] TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression
    Liu, Hou-Pu
    Cao, Anthony T.
    Feng, Ting
    Li, Qingjie
    Zhang, Wenbo
    Yao, Suxia
    Dann, Sara M.
    Elson, Charles O.
    Cong, Yingzi
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2015, 45 (04) : 1010 - 1018
  • [22] TGF-β Signaling Initiated in Dendritic Cells Instructs Suppressive Effects on Th17 Differentiation at the Site of Neuroinflammation
    Speck, Suzanne
    Lim, James
    Shelake, Sagar
    Matka, Marsel
    Stoddard, Jonathan
    Farr, Alexander
    Kuchroo, Vijay
    Laouar, Yasmina
    PLOS ONE, 2014, 9 (07):
  • [23] TRAF6 inhibits Th17 differentiation and TGF-β-mediated suppression of IL-2
    Cejas, Pedro J.
    Walsh, Matthew C.
    Pearce, Erika L.
    Han, Daehee
    Harms, Gretchen M.
    Artis, David
    Turka, Laurence A.
    Choi, Yongwon
    BLOOD, 2010, 115 (23) : 4750 - 4757
  • [24] TGF-β is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23
    Morishima, Noriko
    Mizoguchi, Izuru
    Takeda, Kiyoshi
    Mizuguchi, Junichiro
    Yoshimoto, Takayuki
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 386 (01) : 105 - 110
  • [25] Excess IL-1 Signaling Enhances the Development of Th17 Cells by Downregulating TGF-β-Induced Foxp3 Expression
    Ikeda, Satoshi
    Saijo, Shinobu
    Murayama, Masanori A.
    Shimizu, Kenji
    Akitsu, Aoi
    Iwakura, Yoichiro
    JOURNAL OF IMMUNOLOGY, 2014, 192 (04) : 1449 - 1458
  • [26] Th17 Cells in Cardiovascular Disease
    Yang, Ke
    Liu, Qianqian
    Fan, Aodi
    Lin, Hanqing
    Wang, Xizheng
    Cui, Tianyi
    Fan, Guanwei
    Li, Lan
    CELL BIOCHEMISTRY AND FUNCTION, 2025, 43 (04)
  • [27] Fatty acid synthase regulates the pathogenicity of Th17 cells
    Young, Kathryne E.
    Flaherty, Stephanie
    Woodman, Kaitlyn M.
    Sharma-Walia, Neelam
    Reynolds, Joseph M.
    JOURNAL OF LEUKOCYTE BIOLOGY, 2017, 102 (05) : 1229 - 1235
  • [28] Th17 cell expansion in gastric cancer may contribute to cancer development and metastasis
    Su, Zhaoliang
    Sun, Yingkun
    Zhu, Haitao
    Liu, Yueqin
    Lin, Xin
    Shen, Huiling
    Chen, Jianguo
    Xu, Wenlin
    Xu, Huaxi
    IMMUNOLOGIC RESEARCH, 2014, 58 (01) : 118 - 124
  • [29] Genetic controls of Th17 cell differentiation and plasticity
    Dong, Chen
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2011, 43 (01) : 1 - 6
  • [30] Berberine Suppresses Th17 and Dendritic Cell Responses
    Yang, Yan
    Qi, Jian
    Wang, Qian
    Du, Liping
    Zhou, Yan
    Yu, Hongsong
    Kijlstra, Aize
    Yang, Peizeng
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (04) : 2516 - 2522
12345