Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas

被引:30
|
作者
Kim, Lawrence H. C. [1 ]
Hogeling, Marcia [2 ]
Wargon, Orli [2 ]
Jiwane, Ashish [1 ]
Adams, Susan [1 ]
机构
[1] Sydney Childrens Hosp, Dept Pediat Surg, Randwick, NSW, Australia
[2] Sydney Childrens Hosp, Dept Pediat Dermatol, Randwick, NSW, Australia
关键词
Ulceration; Infantile hemangioma; Propranolol; PULSED-DYE-LASER; CAPILLARY ENDOTHELIAL-CELLS; GROWTH-FACTOR; CLINICAL CHARACTERISTICS; CUTANEOUS HEMANGIOMAS; INFANCY; MANAGEMENT; COMPLICATIONS; INVOLUTION; APOPTOSIS;
D O I
10.1016/j.jpedsurg.2011.01.012
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Infantile hemangioma (IH) is the most common vascular tumor in early childhood. Ulceration is the most frequent complication, and its management can be challenging. We present 6 cases of ulcerated IH at a single pediatric center, which responded to oral propranolol within 2 to 6 weeks. We recommend that oral propranolol therapy be considered for the management of ulcerated IH as first-line treatment. Crown Copyright (C) 2011 Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:759 / 763
页数:5
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