Green synthesis and biological activity of silver-curcumin nanoconjugates

被引：39
作者：
Abdellah, Ahmed M. [1 ]
Sliem, Mahmoud A. [1 ]
Bakr, Mona [1 ,2 ]
Amin, Rehab M. [1 ,2 ]
机构：
[1] Cairo Univ, Natl Inst Laser Enhanced Sci NILE, Giza 12613, Egypt
[2] Cairo Univ, Egypt Nanotechnol Ctr EGNC, El Sheikh Zayed 12588, Egypt
来源：
FUTURE MEDICINAL CHEMISTRY | 2018年 / 10卷 / 22期
关键词：
antibacterial; biosynthesis; cell culture; cytotoxicity; curcumin nanoparticles; green synthesis; silver-curcumin nanoconjugates; silver nanoparticles; GOLD NANOPARTICLES; IN-VITRO; ANTIBACTERIAL; TOXICITY; CELLS; ASSAY; EFFICACY; SOLVENT; GROWTH; LONGA;
D O I：
10.4155/fmc-2018-0152
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Aim: There is an urgent need to develop alternative antimicrobial agents and, one of which is via the use of nanotechnology. Green synthetic routes are recently being replaced for nanoparticles preparation. Methods results: Silver-curcumin nanoconjugates (Ag-CurNCs) were prepared in an eco-friendly method. The prepared nanomaterials were characterized and the photostability was studied under the influence of UV irradiation. Results showed that, the conjugation between curcumin and silver in the nanoform improve the photostability of curcumin. Cytotoxicity was studied on different skin cell lines, and antibacterial activity was investigated against Escherichia coli. Results revealed the antibacterial activity of the prepared nanoconjugates (Ag-CurNCs) with minimal toxicity to skin cells. Conclusion: Silver nanoparticles improve the photostability and antibacterial activity of curcumin, while curcumin helps in preparing biocompatible silver nanoparticles. [GRAPHICS] .
引用
收藏
页码：2577 / 2588
页数：12
相关论文
共 53 条
  • [1] Rapid synthesis of silver nanoparticles using dried medicinal plant of basil
    Ahmad, Naheed
    Sharma, Seema
    Alam, Md. K.
    Singh, V. N.
    Shamsi, S. F.
    Mehta, B. R.
    Fatma, Anjum
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2010, 81 (01) : 81 - 86
  • [2] Exploiting biosynthetic gold nanoparticles for improving the aqueous solubility of metal-free phthalocyanine as biocompatible PDT agent
    Alexeree, Shaimaa M. I.
    Sliem, Mahmoud A.
    El-Balshy, Ragaa M.
    Amin, Rehab M.
    Harith, M. A.
    [J]. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 76 : 727 - 734
  • [3] Rapid and sensitive microplate assay for screening the effect of silver and gold nanoparticles on bacteria
    Amin, Rehab M.
    Mohamed, Mona B.
    Ramadan, Marwa A.
    Verwanger, Thomas
    Krammer, Barbara
    [J]. NANOMEDICINE, 2009, 4 (06) : 637 - 643
  • [4] RETRACTED: Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo (Retracted article. See vol. 102, pg. 143, 2016)
    Anand, Preetha
    Nair, Hareesh B.
    Sung, Bokyung
    Kunnumakkara, Ajaikumar B.
    Yadav, Vivek R.
    Tekmal, Rajeshwar R.
    Aggarwal, Bharat B.
    [J]. BIOCHEMICAL PHARMACOLOGY, 2010, 79 (03) : 330 - 338
  • [5] Bioavailability of silver nanoparticles and ions: from a chemical and biochemical perspective
    Behra, Renata
    Sigg, Laura
    Clift, Martin J. D.
    Herzog, Fabian
    Minghetti, Matteo
    Johnston, Blair
    Petri-Fink, Alke
    Rothen-Rutishauser, Barbara
    [J]. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2013, 10 (87)
  • [6] Curcumin Nanoparticles: Preparation, Characterization, and Antimicrobial Study
    Bhawana
    Basniwal, Rupesh Kumar
    Buttar, Harpreet Singh
    Jain, V. K.
    Jain, Nidhi
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (05) : 2056 - 2061
  • [7] Systemic Administration of Polymeric Nanoparticle-Encapsulated Curcumin (NanoCurc) Blocks Tumor Growth and Metastases in Preclinical Models of Pancreatic Cancer
    Bisht, Savita
    Mizuma, Masamichi
    Feldmann, Georg
    Ottenhof, Niki A.
    Hong, Seung-Mo
    Pramanik, Dipankar
    Chenna, Venugopal
    Karikari, Collins
    Sharma, Rajni
    Goggins, Michael G.
    Rudek, Michelle A.
    Ravi, Rajani
    Maitra, Amarnath
    Maitra, Anirban
    [J]. MOLECULAR CANCER THERAPEUTICS, 2010, 9 (08) : 2255 - 2264
  • [8] Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure-activity relationships and role of ionic silver and oxidative stress
    Carrola, Joana
    Bastos, Veronica
    Jarak, Ivana
    Oliveira-Silva, Rui
    Malheiro, Eliana
    Daniel-da-Silva, Ana L.
    Oliveira, Helena
    Santos, Conceicao
    Gil, Ana M.
    Duarte, Iola F.
    [J]. NANOTOXICOLOGY, 2016, 10 (08) : 1105 - 1117
  • [9] Antibacterial and bioactive silver-containing Na2O • CaO • 2SiO2 glass prepared by sol-gel method
    Catauro, M
    Raucci, MG
    De Gaetano, F
    Marotta, A
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2004, 15 (07) : 831 - 837
  • [10] Chen S, 1998, THIOL DERIVATIZED AG, V5647, P6169
123456