An efficient one-pot synthesis of novel polysubstituted 4-amino-2,3-dihydropyridines

被引：8

作者：

Mahajan, Nitu ^{[1
]}

Sambyal, Ambika ^{[1
]}

Pannu, Ajay P. S. ^{[2
]}

Razdan, T. K. ^{[1
]}

机构：

[1] Univ Jammu, Dept Chem, Jammu 180006, India

[2] GND Univ, Dept Chem, Amritsar 154003, Punjab, India

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 12期

关键词：

Aldehydes; 2,3-Dihydropyridines; Indium triflate; Ketones; Malononitrile; Multi-component reaction; MULTICOMPONENT REACTIONS; CHEMISTRY; 1,4-DIHYDROPYRIDINES; DIHYDROPYRIDINES; ANTAGONISTS;

D O I：

10.1016/j.tetlet.2011.01.017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and efficient one-pot multi-component synthesis of novel polysubstituted 4-amino-2,3-dihydropyridines from carbonyl compounds, malononitrile and acetonitrile, using indium triflate is reported. Acetonitrile acts both as a solvent as well as a substrate. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1265 / 1268

页数：4

共 36 条

[1]

ABRAMOVITCH RA, 1974, PYRIDINE ITS DER 1 S

[2] 2-CYANO DELTA-3 PIPERIDINES .6. A GENERAL-METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF CIS AND TRANS 2,6-DIALKYLPIPERIDINE ALKALOIDS [J].