One-pot three-component protocol for the synthesis of substituted 2-aminothiazoles

被引：7

作者：

Guo, Shanshan ^{[1
]}

Zhao, Donghong ^{[1
]}

Zhu, Yue ^{[1
]}

Yu, Yongping ^{[1
]}

Chen, Wenteng ^{[1
]}

Zhang, Guolin ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Pharmaceut Sci, Zhejiang Prov Key Lab Anticanc Drug Res, Hangzhou 310058, Zhejiang, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2017年 / 47卷 / 19期

基金：

中国国家自然科学基金;

关键词：

2-Aminothiazoles; -nitro-epoxides; cyanamide; multicomponent; sodium sulfide; DERIVATIVES; THIAZOLES; KETONES; IMIDAZOPYRIDINES; ISOTHIOCYANATES; INHIBITORS; THIOUREAS; STRATEGY; DESIGN; AGENTS;

D O I：

10.1080/00397911.2017.1350275

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substituted 2-aminothiazoles have been synthesized from -nitro-epoxides, cyanamide, and sodium sulfide through a facile, three-component, and ecofriendly protocol with good to excellent yields. This reaction was achieved at room temperature without any additives. A possible mechanism has also been proposed. [GRAPHICS] .

引用

页码：1758 / 1764

页数：7

共 50 条

[31] New synthesis of 2-substituted azoles via a three-component one-pot reaction.
Deng, YJ
Hlasta, DJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U47 - U47
[32] ONE-POT PREPARATION OF 2-CHLOROMETHYLDIOXOLANES AND 2-AMINOTHIAZOLES FROM CHLOROMETHYLTRIOXANES
WAKASUGI, T
SUZUKI, F
MIYAKAWA, T
ITSUNO, S
ITO, K
CHEMISTRY LETTERS, 1994, (11) : 2039 - 2042
[33] Three-component one-pot reaction for the synthesis of β-amide ketones
Luo, Yan-Ping
Chen, Qiong
CHEMICAL PAPERS, 2013, 67 (05) : 532 - 537
[34] A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
Pusch, Stefan
Opatz, Till
ORGANIC LETTERS, 2014, 16 (20) : 5430 - 5433
[35] One-Pot Three-Component Approach to the Synthesis of Polyfunctional Pyrazoles
Zhang, Guolin
Ni, Hangcheng
Chen, Wenteng
Shao, Jiaan
Liu, Huan
Chen, Binhui
Yu, Yongping
ORGANIC LETTERS, 2013, 15 (23) : 5967 - 5969
[36] One-pot three-component reaction for the synthesis of α-(aminoethyl)-α,β-enones
Bertozzi, F
Gustafsson, M
Olsson, R
ORGANIC LETTERS, 2002, 4 (24) : 4333 - 4336
[37] AN EFFICIENT THREE-COMPONENT ONE-POT SYNTHESIS OF PYRIMIDOBENZIMIDAZOLE DERIVATIVES
Kumar, Goda Pankaja
Sekhar, Thuraka
Thriveni, Pinnu
Venkateswarlu, Annavarapu
Reddy, Peduri Suresh
HETEROCYCLIC LETTERS, 2021, 11 (02): : 231 - 236
[38] One-pot, three-component synthesis of arylidenesuccinates and related compounds
McCombie, SW
Luchaco, CA
TETRAHEDRON LETTERS, 1997, 38 (33) : 5775 - 5776
[39] One-pot three-component catalytic asymmetric synthesis of homoallylboronates
Ibrahem, Ismail
Afewerki, Samson
Breistein, Palle
Cordova, Armando
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
[40] A novel, one-pot and three-component synthesis of α-quinoxalinyl triphenylphosphoranes
Adib, Mehdi
Sheibani, Esmaeil
Abbasi, Alireza
Bijanzadeh, Hamid Reza
TETRAHEDRON LETTERS, 2007, 48 (07) : 1179 - 1182

← 1 2 3 4 5 →