Rapamycin RPM) Synergizes with CD154 mAb and DST to Promote Long-Term Vascularized Composite Allograft (VCA) Survival, but Prevents Induction of Donor-Specific Tolerance

被引：0
|
作者：
Oh, B.
Furtmueller, G.
Fryer, M.
Grahammer, J.
Schneeberger, S.
Cooney, D.
Raimondi, G.
Brandacher, G.
机构：
[1] CHOP, Philadelphia, PA USA
[2] Univ Penn, Philadelphia, PA 19104 USA
来源：
AMERICAN JOURNAL OF TRANSPLANTATION | 2016年 / 16卷
关键词：
D O I：
暂无
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
A94
引用
收藏
页码：432 / 432
页数：1
相关论文
共 10 条
  • [1] Brief Peritransplant Therapy With CD40L, Donor Splenocyte Transfusion (DST) and Rapamycin (RPM) Causes Long-Term Hindlimb Vascularized Composite Allograft (VCA) Survival Without a Need for Maintenance Immunosuppression
    Wang, Liqing
    Huang, Jianbing
    Han, Rongxiang
    Bhatti, Tricia R.
    Wang, Zhonglin
    Levin, L. Scott
    Levine, Matthew H.
    Hancock, Wayne W.
    TRANSPLANTATION, 2015, 99 : S26 - S26
  • [2] Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival
    Wang, L.
    Samanta, A.
    Huang, J.
    Bhatti, T.
    Wang, Z.
    Han, R.
    Levin, L.
    Levine, M.
    Hancock, W.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2015, 15
  • [3] Use of a Clinically Relevant T-Cell Depletion Strategy (Anti-TCR mAb) to Promote Long-Term Hindlimb Vascularized Composite Allograft (VCA) Survival
    Wang, Liqing
    Huang, Jianbing
    Han, Rongxiang
    Bhatti, Tricia R.
    Wang, Zhonglin
    Levin, L. Scott
    Levine, Matthew H.
    Hancock, Wayne W.
    TRANSPLANTATION, 2015, 99 : S10 - S10
  • [4] Removal of CD4+ cells, but not thymectomy, synergizes with donor-specific transfusion (DST) and Anti-CD154 monoclonal antibody (mAb) treatment to prolong rat islet and skin xenograft survival in mice
    Gordon, EJ
    Markees, TG
    Shultz, LD
    Mordes, JP
    Greiner, DL
    Rossini, AA
    DIABETES, 2000, 49 : A338 - A338
  • [5] Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis
    Shimizu, K
    Schönbeck, U
    Mach, F
    Libby, P
    Mitchell, RN
    JOURNAL OF IMMUNOLOGY, 2000, 165 (06) : 3506 - 3518
  • [6] Donor apoptotic cell-based therapy for effective inhibition of donor-specific memory T and B cells to promote long-term allograft survival in allosensitized recipients
    Dangi, Anil
    Yu, Shuangjin
    Lee, Frances T.
    Burnette, Melanie
    Knechtle, Stuart
    Kwun, Jean
    Luo, Xunrong
    AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 (10) : 2728 - 2739
  • [7] THE EFFECT OF DONOR-SPECIFIC BLOOD-TRANSFUSION, CYCLOSPORINE, AND DIETARY PROSTAGLANDIN PRECURSORS ON RAT CARDIAC ALLOGRAFT SURVIVAL .2. EFFECTIVENESS OF A 24-HOUR INDUCTION PERIOD WITH DST AND CSA IN INDUCING LONG-TERM GRAFT-SURVIVAL
    TCHERVENKOV, JI
    EPSTEIN, MD
    ALEXANDER, JW
    SCHROEDER, TJ
    TRANSPLANTATION, 1989, 47 (01) : 177 - 181
  • [8] EFFECT OF FK-506 AND DONOR-SPECIFIC BLOOD-TRANSFUSION ON THE RAT COMPOSITE TISSUE LIMB ALLOGRAFT AND THE MECHANISM OF LONG-TERM GRAFT-SURVIVAL
    KUROKI, H
    BEAN, MA
    IKUTA, Y
    AKIYAMA, M
    BURGESS, EM
    TRANSPLANTATION PROCEEDINGS, 1993, 25 (01) : 658 - 661
  • [9] Adenoviral-mediated localized CTLA-4Ig gene expression induces long-term allograft pancreas survival and donor-specific immune tolerance in rats
    John Huang
    Journal of Medical Colleges of PLA, 2008, 23 (06) : 313 - 323
  • [10] Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection
    Guillot, C
    Guillonneau, C
    Mathieu, P
    Gerdes, CA
    Ménoret, S
    Braudeau, C
    Tesson, L
    Renaudin, K
    Castro, MG
    Löwenstein, PR
    Anegon, I
    JOURNAL OF IMMUNOLOGY, 2002, 168 (04) : 1600 - 1609
1