Uptake transporter activities in 27 batches of cryopreserved suspended human hepatocytes

被引：0
|
作者：
Oorts, Marlies [1 ]
Nicolai, Johan [1 ]
Tolando, Roberto [2 ]
Richert, Lysiane [3 ]
Augustijns, Patrick [1 ]
Annaert, Pieter [1 ]
机构：
[1] KU Leuven Drug Delivery & Disposit, Dept Pharmaceut & Pharmacol Sci, Leuven, Belgium
[2] BioReclamationIVT, Frankfurt, Germany
[3] KaLy Cell, Strasbourg, France
来源：
DRUG METABOLISM REVIEWS | 2016年 / 48卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P161
引用
收藏
页码：104 / 104
页数：1
相关论文
共 50 条
  • [21] Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans
    Liao, Mingxiang
    Zhu, Qing
    Zhu, Andy
    Gemski, Christopher
    Ma, Bingli
    Guan, Emily
    Li, Albert P.
    Xiao, Guangqing
    Xia, Cindy Q.
    XENOBIOTICA, 2019, 49 (07) : 852 - 862
  • [22] Development of pooled human cryopreserved hepatocytes using a predictive algorithm to target specific metabolic activities
    Ailes, Caitlin
    Lee, Ji Young
    Miller, Ana
    Celsis, Timothy Moeller
    DRUG METABOLISM REVIEWS, 2009, 41 : 112 - 112
  • [23] Utility of Cryopreserved Hepatocytes Suspended in Serum to Predict Hepatic Clearance in Dogs and Monkeys
    Shibata, Yoshihiro
    Kuze, Jiro
    Chiba, Masato
    DRUG METABOLISM AND PHARMACOKINETICS, 2014, 29 (02) : 168 - 176
  • [24] IMPACT OF DONOR DIVERSITY ON PHASE I AND PHASE II ACTIVITIES IN CRYOPRESERVED HUMAN HEPATOCYTES AND HUMAN LIVER MICROSOMES
    Bohl, Christopher
    Brouwer, Kenneth
    Heyward, Scott
    Cottier, Karissa
    Noah, Courtney
    Ogilvie, Brian
    DRUG METABOLISM AND PHARMACOKINETICS, 2024, 55
  • [25] RIBAVIRIN UPTAKE BY PRIMARY HUMAN HEPATOCYTES CORRESPONDS TO EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 EXPRESSION
    Baloch, B. K.
    Chen, L.
    Ilyas, M.
    Irving, W.
    Thomson, B. J.
    GUT, 2011, 60 : A29 - A29
  • [26] Resolving the Distribution-Metabolism Interplay of Eight OATP Substrates in the Standard Clearance Assay with Suspended Human Cryopreserved Hepatocytes
    Nordell, Par
    Winiwarter, Susanne
    Hilgendorf, Constanze
    MOLECULAR PHARMACEUTICS, 2013, 10 (12) : 4443 - 4451
  • [27] UPTAKE AND DEGRADATION OF DESIALYLATED LUTEINIZING-HORMONE BY SUSPENDED HEPATOCYTES
    BLEKEN, A
    TOLLESHAUG, H
    TORJESEN, P
    BERG, T
    BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 720 (02) : 193 - 202
  • [28] UPTAKE OF CHYLE CHOLESTEROL ESTERS AND INTACT TRIGLYCERIDES BY SUSPENDED HEPATOCYTES
    NILSSON, A
    AKESSON, B
    FEBS LETTERS, 1975, 51 (01) : 219 - 224
  • [29] Comparative metabolism of furan in rodent and human cryopreserved hepatocytes
    Peterson, Lisa A.
    Gates, Leah A.
    Phillips, Martin B.
    Matter, Brock A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [30] Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes
    Li, Na
    Badrinarayanan, Akshay
    Li, Xingwen
    Roberts, John
    Hayashi, Mike
    Virk, Manpreet
    Gupta, Anshul
    DRUG METABOLISM AND DISPOSITION, 2020, 48 (10) : 861 - 872
12345