Uptake transporter activities in 27 batches of cryopreserved suspended human hepatocytes

被引：0
|
作者：
Oorts, Marlies [1 ]
Nicolai, Johan [1 ]
Tolando, Roberto [2 ]
Richert, Lysiane [3 ]
Augustijns, Patrick [1 ]
Annaert, Pieter [1 ]
机构：
[1] KU Leuven Drug Delivery & Disposit, Dept Pharmaceut & Pharmacol Sci, Leuven, Belgium
[2] BioReclamationIVT, Frankfurt, Germany
[3] KaLy Cell, Strasbourg, France
来源：
DRUG METABOLISM REVIEWS | 2016年 / 48卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P161
引用
收藏
页码：104 / 104
页数：1
相关论文
共 50 条
  • [1] Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes
    De Bruyn, Tom
    Ye, Zhi-Wei
    Peeters, Annelies
    Sahi, Jasminder
    Baes, Myriam
    Augustijns, Patrick F.
    Annaert, Pieter P.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 43 (04) : 297 - 307
  • [2] Retention of transporter activities in cryopreserved, isolated rat hepatocytes
    Houle, R
    Raoul, J
    Lévesque, JF
    Pang, KS
    Nicoll-Griffith, DA
    Silva, JM
    DRUG METABOLISM AND DISPOSITION, 2003, 31 (04) : 447 - 451
  • [3] Characterization of drug uptake into cryopreserved human hepatocytes
    Loewen, Greg
    Hensley, Tiffini
    Czerwinski, Maciej
    Ogilvie, Brian
    Parkinson, Andrew
    DRUG METABOLISM REVIEWS, 2009, 41 : 111 - 111
  • [4] The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
    Lundquist, Patrik
    Loof, Johan
    Sohlenius-Sternbeck, Anna-Karin
    Floby, Eva
    Johansson, Jenny
    Bylund, Johan
    Hoogstraate, Janet
    Afzelius, Lovisa
    Andersson, Tommy B.
    DRUG METABOLISM AND DISPOSITION, 2014, 42 (03) : 469 - 480
  • [5] CAN TRANSPORTER-EXPRESSING CELLS PREDICT ROSUVASTATIN UPTAKE CLEARANCE IN SUSPENDED OR PLATED HUMAN HEPATOCYTES?
    Kumar, Vineet
    Salphati, Laurent
    Hop, Cornelis E. C. A.
    Rowbottom, Christopher
    Xiao, Guangqing
    Lai, Yurong
    Mathias, Anita
    Chu, Xiaoyan
    Humphreys, W. Griffith
    Liao, Mingxiang
    Chen, Laigao
    Toth, Beata
    Juhasz, Viktoria
    Heyward, Scott
    Unadkat, Jashvant
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : S22 - S23
  • [6] Hepatic uptake of domperidone in rat and human suspended hepatocytes
    Oorts, Marlies
    Richert, Lysiane
    Annaert, Pieter
    DRUG METABOLISM REVIEWS, 2016, 48 : 146 - 146
  • [7] Use of cryopreserved human hepatocytes for drug uptake transport studies
    Houle, R
    Wu, J
    Petosa, A
    Silva, JM
    Nicoll-Griffith, DA
    DRUG METABOLISM REVIEWS, 2004, 36 : 261 - 261
  • [8] Use of selective substrates and inhibitors to rapidly characterise batches of cryopreserved primary human hepatocytes for assessment of active uptake liability in drug discovery and development
    Golding, Melanie
    Light, Oliver
    Williamson, Beth
    Menochet, Karelle
    XENOBIOTICA, 2022, 52 (08) : 868 - 877
  • [9] Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes
    Janneke Keemink
    Neel Deferm
    Tom De Bruyn
    Patrick Augustijns
    Thomas Bouillon
    Pieter Annaert
    The AAPS Journal, 20
  • [10] Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes
    Keemink, Janneke
    Deferm, Neel
    De Bruyn, Tom
    Augustijns, Patrick
    Bouillon, Thomas
    Annaert, Pieter
    AAPS JOURNAL, 2018, 20 (02):
12345