Sexually acquired syphilis Laboratory diagnosis, management, and prevention

被引:53
作者
Forrestel, Amy K. [1 ]
Kovarik, Carrie L. [1 ]
Katz, Kenneth A. [2 ]
机构
[1] Univ Penn, Dept Dermatol, Philadelphia, PA 19104 USA
[2] Kaiser Permanente, Dept Dermatol, San Francisco, CA USA
关键词
dermatology; sexually transmitted disease; syphilis; OF-CARE TEST; HIV-NEGATIVE PATIENTS; TREPONEMA-PALLIDUM; SECONDARY SYPHILIS; SEROLOGICAL RESPONSE; MALIGNANT SYPHILIS; ENHANCED THERAPY; SEROFAST STATE; UNITED-STATES; LUES MALIGNA;
D O I
10.1016/j.jaad.2019.02.074
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The methods used for the laboratory diagnosis of syphilis include direct detection of Treponema pallidum subspecies pallidum and serologic testing. Serologic testing relies on both nontreponemal and treponemal tests. In newly developed reverse-sequence screening algorithms, treponemal tests are performed before nontreponemal tests. The management of syphilis requires appropriate staging, treatment, and follow-up of patients along with the prompt reporting of infections to public health authorities to assist with prevention and control efforts. Benzathine penicillin G remains the treatment of choice for all stages of syphilis. Screening of populations at higher risk for syphilis is recommended by the US Centers for Disease Control and Prevention, the US Preventive Services Task Force, and the World Health Organization. The second article in this continuing medical education series reviews the testing for and the management of sexually acquired syphilis.
引用
收藏
页码:17 / 28
页数:12
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