Mucoepidermoid carcinoma as an unusual cause for recurrent respiratory infections in a child

被引:5
作者
Vogelberg, C
Mohr, B
Fitze, G
Friedrich, K
Hahn, G
Roesner, D
Leupold, W
Suttorp, M
机构
[1] Tech Univ Dresden, Hosp Carl Gustav Carus, Dept Pediat, D-01307 Dresden, Germany
[2] Tech Univ Dresden, Hosp Carl Gustav Carus, Dept Internal Med 1, D-01307 Dresden, Germany
[3] Tech Univ Dresden, Hosp Carl Gustav Carus, Dept Pediat Surg, D-8027 Dresden, Germany
[4] Tech Univ Dresden, Hosp Carl Gustav Carus, Dept Pathol, D-8027 Dresden, Germany
[5] Tech Univ Dresden, Hosp Carl Gustav Carus, Dept Pediat Radiol, D-8027 Dresden, Germany
关键词
mucoepidermoid carcinoma; bronchial tumor; translocation t(11; 9); childhood;
D O I
10.1097/01.mph.0000155120.50936.73
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Recurrent respiratory infections in a 9-year-old girl prompted a chest radiograph and a CT scan, which showed a right middle lobe consolidation. Bronchoscopy revealed a tumor that totally obstructed the middle lobe. Open lung biopsy revealed a low-grade mucoepidermoid carcinoma. Middle and lower right lung lobectomy was performed, followed by an uneventful recovery. Cytogenetic investigation of tumor cells exhibited the translocation t(11;19). This case shows that further diagnostic modalities such as CT scanning should be performed early in children with recurrent lower respiratory tract infections who have suspicious radiographic findings such as persistent atelectasis or recurrent unifocal infiltration. Bronchial mucoepidermoid carcinoma is infrequent, and molecular investigations might shed additional light on the prognosis.
引用
收藏
页码:162 / 165
页数:4
相关论文
共 22 条
  • [1] PRESENTATION OF BRONCHIAL MUCOEPIDERMOID CARCINOMA AS UNILATERAL HYPERLUCENT LUNG
    ALLEN, ED
    MCCOY, KS
    [J]. PEDIATRIC PULMONOLOGY, 1990, 8 (04) : 294 - 297
  • [2] MUCOEPIDERMOID CARCINOMA OF THE TRACHEA AND BRONCHUS - CASE FOR CONSERVATIVE RESECTION
    BREYER, RH
    DAINAUSKAS, JR
    JENSIK, RJ
    FABER, LP
    [J]. ANNALS OF THORACIC SURGERY, 1980, 29 (03) : 197 - 204
  • [3] CONLAN AA, 1978, J THORAC CARDIOV SUR, V76, P369
  • [4] Endobronchial tumours in childhood
    Curtis, JM
    Lacey, D
    Smyth, R
    Carty, H
    [J]. EUROPEAN JOURNAL OF RADIOLOGY, 1998, 29 (01) : 11 - 20
  • [5] Mucoepidermoid carcinoma of the bronchus
    Dinopoulos, A
    Lagona, E
    Stinios, I
    Konstadinidou, A
    Kattamis, C
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2000, 17 (05) : 401 - 408
  • [6] A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality
    ElNaggar, AK
    Lovell, M
    Killary, AM
    Clayman, GL
    Batsakis, JG
    [J]. CANCER GENETICS AND CYTOGENETICS, 1996, 87 (01) : 29 - 33
  • [7] Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors
    Enlund, F
    Behboudi, A
    Andrén, Y
    Öberg, C
    Lendahl, U
    Mark, J
    Stenman, G
    [J]. EXPERIMENTAL CELL RESEARCH, 2004, 292 (01) : 21 - 28
  • [8] Mucoepidermoid carcinoma of the bronchus presenting with a negative chest X-ray and normal pulmonary function in two teenagers: Two case reports and review of the literature
    Giusti, RJ
    Flores, RM
    [J]. PEDIATRIC PULMONOLOGY, 2004, 37 (01) : 81 - 84
  • [9] Granata C, 1997, PEDIATR PULM, V23, P226, DOI 10.1002/(SICI)1099-0496(199703)23:3<226::AID-PPUL10>3.0.CO
  • [10] 2-9