Apaziquone for Nonmuscle Invasive Bladder Cancer Where Are We Now?

被引：6

作者：

Arends, Tom J. H. ^{[1
]}

Witjes, Johannes Alfred ^{[2
]}

机构：

[1] Canisius Wilhelmina Hosp, Dept Urol, Weg Door Jonkerbos 100, NL-6532 SZ Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, Dept Urol, Geert Groote Pl Zuid 10, NL-6525 GA Nijmegen, Netherlands

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2020年 / 47卷 / 01期

关键词：

Apaziquone; Bladder cancer; Nonmuscle invasive; Therapy; Experimental; BACILLUS-CALMETTE-GUERIN; CARCINOMA IN-SITU; TRANSITIONAL-CELL CARCINOMA; HEXAMINOLEVULINATE FLUORESCENCE CYSTOSCOPY; BIOREDUCTIVE ALKYLATING INDOLOQUINONE; INTRAVESICAL GEMCITABINE THERAPY; 2ND TRANSURETHRAL RESECTION; WHITE-LIGHT CYSTOSCOPY; II MARKER LESION; PHASE-III;

D O I：

10.1016/j.ucl.2019.09.009

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Apaziquone is an interesting drug for intravesical use in patients with nonmuscle invasive bladder cancer; however, more research is needed to prove its actual benefit. Although the apaziquone trials demonstrate the potential of this new drug, the singular phase 3 trials did not reach their primary endpoint. To date, no new trials are recruiting, so the development of apaziquone seems to have stopped.

引用

页码：73 / +

页数：11

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