Three-Dimensional Transthoracic Static and Dynamic Normative Values of the Mitral Valve Apparatus: Results from the Multicenter World Alliance Societies of Echocardiography Study

被引：12

作者：

Henry, Michael P. ^{[1
]}

Cotella, Juan ^{[1
]}

Mor-Avi, Victor ^{[1
]}

Addetia, Karima ^{[1
]}

Miyoshi, Tatsuya ^{[2
]}

Schreckenberg, Marcus ^{[3
]}

Blankenhagen, Michael ^{[3
]}

Hitschrich, Niklas ^{[3
]}

Amuthan, Vivekanandan ^{[4
]}

Citro, Rodolfo ^{[5
]}

Daimon, Masao ^{[6
]}

Gutierrez-Fajardo, Pedro ^{[7
]}

Kasliwal, Ravi ^{[8
]}

Kirkpatrick, James N. ^{[9
]}

Monaghan, Mark J. ^{[10
]}

Muraru, Denisa ^{[11
,12
]}

Ogunyankin, Kofo O. ^{[13
]}

Park, Seung Woo ^{[14
]}

Rodrigues, Ana Clara Tude ^{[15
]}

Ronderos, Ricardo ^{[16
]}

Sadeghpour, Anita ^{[17
]}

Scalia, Gregory ^{[18
]}

Takeuchi, Masaaki ^{[19
]}

Tsang, Wendy ^{[20
]}

Tucay, Edwin S. ^{[21
]}

Zhang, Mei ^{[22
]}

Lang, Roberto M. ^{[1
]}

Asch, Federico M. ^{[2
]}

机构：

[1] Univ Chicago, Chicago, IL 60637 USA

[2] MedStar Hlth Res Inst, Washington, DC USA

[3] TomTec Imaging Syst, Unterschleissheim, Germany

[4] Jeyalakshmi Heart Ctr, Madurai, Tamil Nadu, India

[5] Univ Salerno, Salerno, Italy

[6] Univ Tokyo, Tokyo, Japan

[7] Hosp Mac Bernardette, Guadalajara, Jalisco, Mexico

[8] Medanta Heart Inst, Gurgaon, India

[9] Univ Washington, Seattle, WA 98195 USA

[10] Kings Coll Hosp London, London, England

[11] San Luca Hosp, Inst Auxol Italiano, IRCCS, Milan, Italy

[12] Univ Milano Bicocca, Milan, Italy

[13] First Cardiol Consultants Hosp, Lagos, Nigeria

[14] Samsung Med Ctr, Seoul, South Korea

[15] Albert Einstein Hosp, Sao Paulo, Brazil

[16] Inst Cardiovasc Buenos Aires, Buenos Aires, DF, Argentina

[17] Rajaie Cardiovasc Med & Res Ctr, Tehran, Iran

[18] Genesis Care, Brisbane, Qld, Australia

[19] Univ Occupat & Environm Hlth, Kitakyushu, Fukuoka, Japan

[20] Univ Toronto, Toronto Gen Hosp, Toronto, ON, Canada

[21] Philippine Heart Ctr, Quezon City, Philippines

[22] Shandong Univ, Qilu Hosp, Jinan, Peoples R China

来源：

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | 2022年 / 35卷 / 07期

关键词：

Three-dimensional echocardiography; Normal values; Mitral annulus; Mitral leaflets; AMERICAN SOCIETY; ANNULAR DYNAMICS; REGURGITATION; QUANTIFICATION; INSIGHTS; RECOMMENDATIONS; PARAMETERS; PROLAPSE; ANATOMY; DISEASE;

D O I：

10.1016/j.echo.2022.02.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Recent advances in mitral valve (MV) percutaneous interventions have escalated the need for a more quantitative and comprehensive assessment of the MV, which can be best achieved using three-dimensional echocardiography. Understanding normal valve size, structure, and function is essential for differentiation of healthy from disease states. The aims of this study were to establish normative values for MV apparatus size and morphology and to determine how they vary across age, sex, and race groups using data from the World Alliance Societies of Echocardiography Normal Values Study. Methods: Three-dimensional volumetric data sets obtained on transthoracic echocardiography in 748 normal subjects (51% men) were analyzed using commercial MV analysis software (TomTec Imaging Systems) to determine annular and leaflet dimensions and areas. The subjects were divided into groups by sex (378 men and 370 women) and age (18 to 40 years [n = 266], 41 to 65 years [n = 249], and >65 years [n = 233]) to identify sex- and age-related differences. In addition, differences among black, white, and Asian populations were studied. Inter- and intraobserver variability was assessed in a subset of 30 subjects and expressed as mean absolute difference between pairs of repeated measurements. Results: Compared with women, men had larger annular size measurements, larger tenting size parameters, and larger leaflet length and area. Compared with the black and white populations, the Asian population showed significantly smaller mitral annular size. Although many of the age, sex, and race differences in MV parameters were statistically significant, they were comparable with or smaller than the corresponding measurement variability. Indexing to body surface area and height did not eliminate these differences consistently, suggesting that parameters may need to be indexed according to their dimensionality. Conclusions: This analysis of the World Alliance Societies of Echocardiography data provides normative values of mitral apparatus size and morphology. Although sex- and age-related differences were noted, they need to be interpreted with caution in view of the associated measurement variability. (J Am Soc Echocardiogr 2022;35:738-51.)

引用

页码：738 / +

页数：15

共 47 条

[31] Systolic characteristics and dynamic changes of the mitral valve in different grades of ischemic mitral regurgitation - insights from 3D transesophageal echocardiography [J].