Complications and oncologic outcomes following elective neck dissection with salvage laryngectomy for the N0 neck

被引:32
作者
Freiser, Monika E. [1 ,3 ]
Ojo, Rosemary B. [1 ,4 ]
Lo, Kaming [2 ]
Saint-Victor, Sandra [1 ]
Bollig, Craig [1 ,5 ]
Nayak, Chetan S. [1 ]
Sargi, Zoukaa B. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Otolaryngol, 1120 NW 14th St,Suite 650D, Miami, FL 33136 USA
[2] Univ Miami, Miller Sch Med, Dept Publ Hlth Sci, Biostat Collaborat & Consulting Core,Div Biostat, 1120 NW 14th St,Suite 1049, Miami, FL USA
[3] Univ Pittsburgh, Med Ctr, Dept Otolaryngol, 203 Lothrop St, Pittsburgh, PA 15213 USA
[4] Silverstein Inst, 1901 Floyd St, Sarasota, FL 34239 USA
[5] Univ Missouri, Sch Med, Dept Otolaryngol, 1 Hosp Dr,MA 314, Columbia, MO 65212 USA
关键词
LOCALLY RECURRENT HEAD; PHARYNGOCUTANEOUS FISTULA; DECISION-ANALYSIS; NODAL DISEASE; SURGERY; MANAGEMENT; RADIOTHERAPY;
D O I
10.1016/j.amjoto.2016.01.004
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Purpose: To investigate the difference in survival and complication outcomes between patients with a clinically and radiologically N0 neck who received an elective neck dissection at the time of salvage total laryngectomy compared to those who had salvage total laryngectomy alone. Materials and methods: A retrospective chart review was performed on 125 salvage total laryngectomy patients who were clinically and radiologically N0 preoperatively. Performance of an elective neck dissection and other factors were tested for associations with various postoperative complications, disease-free survival, and overall survival. Results: Ninety-eight patients underwent elective neck dissection, of which ten had positive nodal pathology. Elective neck dissection was not significantly associated with complications or survival outcomes. Positive nodal disease was associated with worse disease-free and overall survival on multivariate analysis. Conclusions: In patients with clinically and radiologically N0 necks undergoing salvage total laryngectomy, an elective neck dissection can provide prognostic information but does not appear to be significantly associated with increased complications or improved survival. (c) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:186 / 194
页数:9
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