In situ hybridization of PNA/DNA studied label-free by electrochemical impedance spectroscopy

被引：85
|
作者：
Liu, JY
Tian, SJ
Nielsen, PE
Knoll, W
机构：
[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany
[2] Univ Copenhagen, Panum Inst, Ctr Biochem Recognit, Dept Biochem & Genet,Biochem Lab B, DK-2200 Copenhagen, Denmark
来源：
CHEMICAL COMMUNICATIONS | 2005年 / 23期
关键词：
D O I：
10.1039/b419425j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The in situ hybridization kinetics of label-free DNA on mixed monolayers of peptide nucleic acid (PNA) and 6-mercapto-1-hexanol (MCH) on Au electrodes was investigated by electrochemical impedance spectroscopy (EIS) and used to discriminate the fully complementary DNA from the single-base mismatched hybrids.
引用
收藏
页码：2969 / 2971
页数：3
相关论文
共 50 条
  • [31] Label-free detection of bacteria by electrochemical impedance spectroscopy: Comparison to surface plasmon resonance
    Maalouf, Rita
    Fournier-Wirth, Chantal
    Coste, Joliette
    Chebib, Hanna
    Saikali, Youssef
    Vittori, Olivier
    Errachid, Abdelhamid
    Cloarec, Jean-Pierre
    Martelet, Claude
    Jaffrezic-Renault, Nicole
    ANALYTICAL CHEMISTRY, 2007, 79 (13) : 4879 - 4886
  • [32] Label-Free Toxin Detection by Means of Time-Resolved Electrochemical Impedance Spectroscopy
    Chai, Changhoon
    Takhistov, Paul
    SENSORS, 2010, 10 (01) : 655 - 669
  • [33] A methodology for rapid detection of Salmonella typhimurium using label-free electrochemical impedance spectroscopy
    Nandakumar, Vivek
    La Belle, Jeffrey T.
    Reed, Justin
    Shah, Miti
    Cochran, Douglas
    Joshi, Lokesh
    Alford, T. L.
    BIOSENSORS & BIOELECTRONICS, 2008, 24 (04): : 1039 - 1042
  • [34] Label-Free Electrochemical Detection of DNA Hybridization: A Method for COVID-19 Diagnosis
    Suryasnata Tripathy
    Shiv Govind Singh
    Transactions of the Indian National Academy of Engineering, 2020, 5 (2) : 205 - 209
  • [35] Label-Free Electrochemical Detection of MicroRNAs via Intercalation of Hemin into the DNA/RNA Hybridization
    Yi, Xinyao
    Lu, Zhixuan
    Kong, Yu
    Chen, Zhuo
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2017, 12 (04): : 2813 - 2821
  • [36] Label-free electrochemical recognition of DNA hybridization by means of modulation of the feedback current in SECM
    Turcu, F
    Schulte, A
    Hartwich, G
    Schuhmann, W
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (26) : 3482 - 3485
  • [37] Improved electrochemical performances of polyaniline nanotubes-poly-L-lysine composite for label-free impedance detection of DNA hybridization
    YANG Tao
    College of Chemistry and Molecular Engineering
    Science China(Chemistry), 2010, (06) : 1371 - 1377
  • [38] Improved electrochemical performances of polyaniline nanotubes-poly-L-lysine composite for label-free impedance detection of DNA hybridization
    Yang Tao
    Jiang Chen
    Zhang Wei
    Jiao Kui
    SCIENCE CHINA-CHEMISTRY, 2010, 53 (06) : 1371 - 1377
  • [39] Pencil-based renewable biosensor for label-free electrochemical detection of DNA hybridization
    Wang, J
    Kawde, AN
    ANALYTICA CHIMICA ACTA, 2001, 431 (02) : 219 - 224
  • [40] Improved electrochemical performances of polyaniline nanotubes-poly-L-lysine composite for label-free impedance detection of DNA hybridization
    Tao Yang
    Chen Jiang
    Wei Zhang
    Kui Jiao
    Science China Chemistry, 2010, 53 : 1371 - 1377
12345