In situ hybridization of PNA/DNA studied label-free by electrochemical impedance spectroscopy

被引：85
|
作者：
Liu, JY
Tian, SJ
Nielsen, PE
Knoll, W
机构：
[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany
[2] Univ Copenhagen, Panum Inst, Ctr Biochem Recognit, Dept Biochem & Genet,Biochem Lab B, DK-2200 Copenhagen, Denmark
来源：
CHEMICAL COMMUNICATIONS | 2005年 / 23期
关键词：
D O I：
10.1039/b419425j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The in situ hybridization kinetics of label-free DNA on mixed monolayers of peptide nucleic acid (PNA) and 6-mercapto-1-hexanol (MCH) on Au electrodes was investigated by electrochemical impedance spectroscopy (EIS) and used to discriminate the fully complementary DNA from the single-base mismatched hybrids.
引用
收藏
页码：2969 / 2971
页数：3
相关论文
共 50 条
  • [1] Optimization of label-free DNA detection with electrochemical impedance spectroscopy using PNA probes
    Keighley, Simon D.
    Estrela, Pedro
    Li, Peng
    Mighorato, Piero
    BIOSENSORS & BIOELECTRONICS, 2008, 24 (04): : 906 - 911
  • [2] Label-Free Detection of DNA Hybridization in Presence of Intercalators Using Electrochemical Impedance Spectroscopy
    Gebala, Magdalena
    Stoica, Leonard
    Neugebauer, Sebastian
    Schuhmann, Wolfgang
    ELECTROANALYSIS, 2009, 21 (3-5) : 325 - 331
  • [3] Label-free electrochemical impedance sensing of DNA hybridization based on functionalized graphene sheets
    Hu, Yuwei
    Li, Fenghua
    Bai, Xiaoxue
    Li, Dan
    Hua, Shucheng
    Wang, Kaikai
    Niu, Li
    CHEMICAL COMMUNICATIONS, 2011, 47 (06) : 1743 - 1745
  • [4] A label-free DNA sensor based on impedance spectroscopy
    Kafka, J.
    Paenke, O.
    Abendroth, B.
    Lisdat, F.
    ELECTROCHIMICA ACTA, 2008, 53 (25) : 7467 - 7474
  • [5] Label-free detection of protein-DNA interactions using electrochemical impedance spectroscopy
    Tersch, C.
    Lisdat, F.
    ELECTROCHIMICA ACTA, 2011, 56 (22) : 7673 - 7679
  • [6] Optimization of DNA immobilization on gold electrodes for label-free detection by electrochemical impedance spectroscopy
    Keighley, Simon D.
    Li, Peng
    Estrela, Pedro
    Mighorato, Piero
    BIOSENSORS & BIOELECTRONICS, 2008, 23 (08): : 1291 - 1297
  • [7] DNA hybridization detection by label free versus impedance amplifying label with impedance spectroscopy
    Ma, KS
    Zhou, H
    Zoval, J
    Madou, M
    SENSORS AND ACTUATORS B-CHEMICAL, 2006, 114 (01) : 58 - 64
  • [8] Label-free electrochemical detection of DNA hybridization on gold electrode
    Kerman, K
    Morita, Y
    Takamura, Y
    Tamiya, E
    ELECTROCHEMISTRY COMMUNICATIONS, 2003, 5 (10) : 887 - 891
  • [9] Development of an enrofloxacin immunosensor based on label-free electrochemical impedance spectroscopy
    Wu, Ching-Chou
    Lin, Chia-Hung
    Wang, Way-Shyan
    TALANTA, 2009, 79 (01) : 62 - 67
  • [10] Label-Free Telomerase Activity Detection via Electrochemical Impedance Spectroscopy
    Diaz-Cartagena, Diana C.
    Hernandez-Cancel, Griselle
    Bracho-Rincon, Dina
    Gonzalez-Feliciano, Jose A.
    Cunci, Lisandro
    Gonzalez, Carlos, I
    Cabrera, Carlos R.
    ACS OMEGA, 2019, 4 (16): : 16724 - 16732
12345