Microfluidic separation of DNA

被引：36
作者：
Ashton, R [1 ]
Padala, C [1 ]
Kane, RS [1 ]
机构：
[1] Rensselaer Polytech Inst, Howard P Isermann Dept Chem Engn, Troy, NY 12180 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 05期
关键词：
D O I：
10.1016/S0958-1669(03)00113-7
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
DNA separation is important for numerous applications in biotechnology and medicine. Efforts to improve DNA separation in microdevices have led to advances in capillary electrophoresis and the development of novel separation strategies. Current research on microcapillary electrophoresis materials is focused on the development of separation matrices with low injection viscosities and wall-coating capabilities. Microcapillary injector geometries are being designed to allow increased control of sample plug volumes. Novel separation strategies using entropic traps, arrays of pillars and Brownian ratchets are also being developed.
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收藏
页码：497 / 504
页数：8
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