Characteristics and management of Uveitis-Glaucoma-Hyphema syndrome

Introduction. - Uveitis-Glaucoma-Hyphema syndrome (UGH) is caused by mechanical chafing of anterior segment structures by an intraocular lens, especially an anterior chamber tens. The objective of this study was to characterise the clinical course and risk factors of UGH syndrome at a time when posterior chamber implantation is the gold standard. Patients and methods. - This was a retrospective study of 30 cases of UGH syndrome managed between January 2014 and September 2018. Data from the initial clinical examination, the type of implant involved and the clinical management were analysed. Results. - Thirty eyes of 28 patients were included. Intl-a ocular lenses were iris-sutured (15/30, 50 %), in the bag (6/30, 20 %), scleral-fixated (4/30, 13.3 %), in the ciliary sulcus (3/30,10 %) or "in and out" (2/30, 6.7 %). Initial management was medical (18 eyes) or surgical (12 eyes). Surgical procedures were explantation (n =4), IOL repositioning (n =7) or trabeculectomy (n = 1). Recurrences occurred with medical treatment (9/18), but not in the surgical group (p= 0.02). Ocular hypertension became chronic in 19 cases out of 30 (63.3 %). Conclusion. - UGH syndrome can be caused by any type of pseudophakic tens. An intraocular lens in the bag should not rule out the diagnosis. Despite the decreasing popularity of anterior chamber intraocular lens implantation, UGH syndrome remains a current condition and must be recognised in order to adapt therapeutic management. (C) 2020 Elsevier Masson SAS. All rights reserved.