Accuracy and precision of methods to estimate the number of parents contributing to a half-sib progeny array

被引:24
作者
Fiumera, AC [1 ]
DeWoody, YD [1 ]
DeWoody, JA [1 ]
Asmussen, MA [1 ]
Avise, JC [1 ]
机构
[1] Univ Georgia, Dept Genet, Athens, GA 30602 USA
关键词
D O I
10.1093/jhered/92.2.120
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Molecular technologies have made feasible large-scale studies of genetic parentage in nature by permitting the genotypic examination of hundreds or thousands of progeny. One common goal of such studies is to estimate the true number of unshared parents who contributed to a large half-sib progeny array. Here we introduce computer programs designed to count the number of gametotypes contributed by unshared parents to each such progeny array, as well as assess the accuracy and precision of various estimators for the true number of unshared parents via computer simulation. These simulations indicate that under most biological conditions (1) a traditional approach (the multilocus MINIMUM METHOD) that merely counts the number of distinct haplotypes in offspring and divides by 2(L), where L is the number of loci assayed, often vastly underestimates the true number of unshared parents who contributed to a half-sib progeny array; (2) a recently developed HAPLOTYPES estimator is a considerable improvement over the MINIMUM METHOD when parental numbers are high; and (3) the accuracy and precision of the HAPLOTYPES estimator increase as marker polymorphism and sample size increase, or as reproductive skew and the number of parents contributing to the progeny array decrease, Generally, HAPLOTYPES-based estimates of parental numbers in large half-sib cohorts should improve the characterization of organismal reproductive strategies and mating systems from genetic data.
引用
收藏
页码:120 / 126
页数:7
相关论文
共 18 条
[11]  
2
[12]  
Jones AG, 1998, EVOLUTION, V52, P848, DOI 10.1111/j.1558-5646.1998.tb03709.x
[13]   Intraspecific brood mixing and reduced polyandry in a maternal mouth-brooding cichlid [J].
Kellogg, KA ;
Markert, JA ;
Stauffer, JR ;
Kocher, TD .
BEHAVIORAL ECOLOGY, 1998, 9 (03) :309-312
[14]  
Kichler K, 1999, MOL ECOL, V8, P819
[15]   POPULATION-GENETICS OF MEXICAN DROSOPHILA .5. A HIGH-RATE OF MULTIPLE INSEMINATION IN A NATURAL-POPULATION OF DROSOPHILA-PSEUDOOBSCURA [J].
LEVINE, L ;
ASMUSSEN, M ;
OLVERA, O ;
POWELL, JR ;
DELAROSA, ME ;
SALCEDA, VM ;
GASO, MI ;
GUZMAN, J ;
ANDERSON, WW .
AMERICAN NATURALIST, 1980, 116 (04) :493-503
[16]   Statistical confidence for likelihood-based paternity inference in natural populations [J].
Marshall, TC ;
Slate, J ;
Kruuk, LEB ;
Pemberton, JM .
MOLECULAR ECOLOGY, 1998, 7 (05) :639-655
[17]   Polygynandry in Pseudotropheus zebra, a cichlid fish from Lake Malawi [J].
Parker, A ;
Kornfield, I .
ENVIRONMENTAL BIOLOGY OF FISHES, 1996, 47 (04) :345-352
[18]   SNEAKERS, SATELLITES, AND HELPERS - PARASITIC AND COOPERATIVE BEHAVIOR IN FISH REPRODUCTION [J].
TABORSKY, M .
ADVANCES IN THE STUDY OF BEHAVIOR, VOL 23, 1994, 23 :1-100